Klebsiella pneumoniae strain SIKP132 141_NODE_82

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP132 141_NODE_82 is a Gram-negative, rod-shaped bacterium that exhibits multiple cellular arrangements, including chains, pairs, and singles. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic conditions, and relies on chemoheterotrophy as its energy source. This strain possesses flagella, indicating motility, and is classified as mesophilic, with an optimal growth temperature of 37°C. SIKP132 141_NODE_82 is primarily host-associated, with a wide range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other vertebrates and invertebrates. This bacterium is known for its pathogenicity in humans, where it can cause a variety of serious health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis. These infections can manifest in numerous forms, including cystitis, intra-abdominal infections, and neonatal sepsis, highlighting the strain’s clinical significance. The presence of two membranes suggests a complex structure typical of Gram-negative bacteria, and the lack of sporulation indicates that it does not form spores, which may influence its survival strategies in host environments. The extensive range of health effects associated with Klebsiella pneumoniae strain SIKP132 emphasizes its role as a free-living organism that can adapt to various biological niches, making it a significant concern in both clinical and ecological contexts. Understanding the traits and behaviors of this strain can inform strategies for managing infections it causes and understanding its ecological interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP132 141_NODE_82

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP132 141_NODE_82
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP132 141_NODE_82, whole genome

Gene Summary

Adenine Count

1182567 bp

Thymine Count

1175276 bp

Guanine Count

1570062 bp

Cytosine Count

1586964 bp

Genome Length

5514869 bp

Protein-coding Genes

5094 genes

Non-Coding Genes

351 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
two-component system sensor histidine kinase dcusFAS43_00225Not AvailableNegative47839 - 4945558938.6
hypothetical proteinFAS43_00230Not AvailablePositive49611 - 4996713949.2
n-acetylmuramic acid 6-phosphate etheraseFAS43_00235Not AvailablePositive50131 - 5105132755.3
malate dehydrogenase (quinone)FAS43_00240Not AvailablePositive51315 - 5297060305.8
lysr family transcriptional regulatorFAS43_00245Not AvailablePositive53128 - 5405434652.3
malonate decarboxylase subunit epsilonFAS43_00250Not AvailableNegative54044 - 5494632187.1
malonate decarboxylase holo-acp synthaseFAS43_00255Not AvailableNegative54946 - 5556323015.5
aec family transporterFAS43_00260Not AvailableNegative55567 - 5652633332.4
biotin-independent malonate decarboxylase subunit gammaFAS43_00265Not AvailableNegative56663 - 5746328194.8
biotin-independent malonate decarboxylase subunit betaFAS43_00270Not AvailableNegative57463 - 5829629723.5

Displaying genes 351 – 360 of 5445 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total