Klebsiella pneumoniae strain SIKP132 141_NODE_82

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP132 141_NODE_82 is a Gram-negative, rod-shaped bacterium that exhibits multiple cellular arrangements, including chains, pairs, and singles. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic conditions, and relies on chemoheterotrophy as its energy source. This strain possesses flagella, indicating motility, and is classified as mesophilic, with an optimal growth temperature of 37°C. SIKP132 141_NODE_82 is primarily host-associated, with a wide range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other vertebrates and invertebrates. This bacterium is known for its pathogenicity in humans, where it can cause a variety of serious health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis. These infections can manifest in numerous forms, including cystitis, intra-abdominal infections, and neonatal sepsis, highlighting the strain’s clinical significance. The presence of two membranes suggests a complex structure typical of Gram-negative bacteria, and the lack of sporulation indicates that it does not form spores, which may influence its survival strategies in host environments. The extensive range of health effects associated with Klebsiella pneumoniae strain SIKP132 emphasizes its role as a free-living organism that can adapt to various biological niches, making it a significant concern in both clinical and ecological contexts. Understanding the traits and behaviors of this strain can inform strategies for managing infections it causes and understanding its ecological interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP132 141_NODE_82

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP132 141_NODE_82
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP132 141_NODE_82, whole genome

Gene Summary

Adenine Count

1182567 bp

Thymine Count

1175276 bp

Guanine Count

1570062 bp

Cytosine Count

1586964 bp

Genome Length

5514869 bp

Protein-coding Genes

5094 genes

Non-Coding Genes

351 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Repressor ciFAS43_26115Not AvailableNegative5231442 - 523224529894.6
Hypothetical proteinFAS43_26120Not AvailablePositive5232499 - 523321227374.6
Antirepressor proteinFAS43_26125Not AvailablePositive5233282 - 523403427483.0
Hypothetical proteinFAS43_26130Not AvailablePositive5234189 - 523454813715.4
Hypothetical proteinFAS43_26135Not AvailablePositive5234628 - 52348408066.95
hypothetical proteinFAS43_26140Not AvailablePositive5234915 - 523594337404.6
Tail length tape measure proteinFAS43_26145Not AvailablePositive5236009 - 5239425119611.0
rrf2 family transcriptional regulatorFAS43_26150Not AvailablePositive5239466 - 52396456587.89
duf1883 domain-containing proteinFAS43_26155Not AvailableNegative5239622 - 52398889959.82
Hypothetical proteinFAS43_26160Not AvailablePositive5240059 - 524047815954.7

Displaying genes 291 – 300 of 5445 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total