Klebsiella pneumoniae strain SIKP131 140_NODE_77

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP131 140_NODE_77 is a Gram-negative, rod-shaped bacterium that demonstrates a range of pathogenic effects in humans and other hosts. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic range. SIKP131 is characterized as a chemoheterotroph, relying on organic compounds for energy and carbon. Its habitat is primarily host-associated, and it exhibits a free-living biotic relationship, indicating a degree of environmental adaptability. The strain has been implicated in several severe health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. These health effects highlight its pathogenic potential, particularly in human hosts, but it can also affect a variety of other species, including domestic animals and plants. The strain possesses a single replicon and two membranes, features typical of Gram-negative bacteria. The wide host range—encompassing Homo sapiens, Gallus gallus, and various other animal and plant taxa—suggests that Klebsiella pneumoniae SIKP131 may play a significant role in both human health and ecological contexts. Its ability to cause infections across multiple species emphasizes the importance of monitoring such pathogens in both clinical and environmental settings, underscoring their relevance in public health and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP131 140_NODE_77

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP131 140_NODE_77
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP131 140_NODE_77, whole genome

Gene Summary

Adenine Count

1178892 bp

Thymine Count

1180183 bp

Guanine Count

1589160 bp

Cytosine Count

1569204 bp

Genome Length

5517439 bp

Protein-coding Genes

5102 genes

Non-Coding Genes

356 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinFAS54_02990Not AvailableNegative593917 - 59423111786.1
Trna-arg;Not AvailableNot AvailablePositive594500 - 594576Not Available
Trna-thr;Not AvailableNot AvailablePositive594582 - 594657Not Available
Trna-phe;Not AvailableNot AvailablePositive594663 - 594738Not Available
Trna-asn;Not AvailableNot AvailablePositive594745 - 594819Not Available
Q antitermination proteinFAS54_03015Not AvailableNegative594996 - 59549619233.2
Conserved hypothetical bacteriophage proteinFAS54_03020Not AvailableNegative595493 - 5956335613.93
Dna junction-specific endonuclease rapFAS54_03025Not AvailableNegative595630 - 59626524242.6
NineFAS54_03030Not AvailableNegative596258 - 5964286678.42
Ninb proteinFAS54_03035Not AvailableNegative596409 - 59687618105.6

Displaying genes 41 – 50 of 5458 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total