Klebsiella pneumoniae strain SIKP158 167_NODE_88

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP158 167_NODE_88 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph, thriving optimally at 37°C within a mesophilic temperature range. This strain exhibits a diverse cellular arrangement, typically found in chains, pairs, and singles, and possesses flagella, contributing to its mobility. K. pneumoniae SIKP158 is associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and other metazoans, demonstrating its versatility in colonizing a range of species, including mammals, birds, and even plants. The strain is known for its pathogenic potential, causing numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections, among others. The wide range of diseases it can induce highlights its significance in clinical microbiology. This strain is nonsporulating and has a single replicon with two membranes, characteristics typical of many Gram-negative bacteria. Its free-living biotic relationship indicates that it can exist independently in different environments, potentially influencing its adaptability. The ecological insight gleaned from this strain's adaptability to diverse hosts and environments underscores the importance of K. pneumoniae in both health and disease. Its capability to thrive in various conditions and its associated pathogenicity make it a significant focus for understanding microbial interactions within host ecosystems and for addressing public health challenges related to infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP158 167_NODE_88

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP158 167_NODE_88
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP158 167_NODE_88, whole genome

Gene Summary

Adenine Count

1173130 bp

Thymine Count

1183715 bp

Guanine Count

1591772 bp

Cytosine Count

1563997 bp

Genome Length

5512614 bp

Protein-coding Genes

5144 genes

Non-Coding Genes

308 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nark family nitrate/nitrite mfs transporterFAQ88_03335Not AvailablePositive648688 - 65007049450.4
nitrate reductase subunit alphaFAQ88_03340Not AvailablePositive650185 - 653925139856.0
nitrate reductase subunit betaFAQ88_03345Not AvailablePositive653922 - 65546658442.8
nitrate reductase molybdenum cofactor assembly chaperoneFAQ88_03350Not AvailablePositive655466 - 65616126051.1
respiratory nitrate reductase subunit gammaFAQ88_03355Not AvailablePositive656158 - 65683825835.2
n-hydroxyarylamine o-acetyltransferaseFAQ88_03360Not AvailableNegative657505 - 65835032087.1
iron abc transporter permeaseFAQ88_03365Not AvailableNegative658427 - 66008258244.8
extracellular solute-binding proteinFAQ88_03370Not AvailableNegative660140 - 66110834089.9
abc transporter atp-binding proteinFAQ88_03375Not AvailableNegative661105 - 66180625397.9
flavin reductase family proteinFAQ88_03380Not AvailablePositive662021 - 66260221289.2

Displaying genes 831 – 840 of 5452 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total