Klebsiella pneumoniae strain SIKP063 68_NODE_78

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP063 68_NODE_78 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and chemoheterotroph. This strain commonly exists in pairs, chains, or as single cells and possesses flagella, contributing to its mobility. It thrives optimally at a temperature of 37°C, falling within the mesophilic range, and is associated with various hosts, including Homo sapiens, Gallus gallus, and Sus scrofa, among others. This strain is a free-living organism that plays a significant role in human health, being linked to a variety of serious infections. Notably, it has been implicated in conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. The range of health effects associated with this strain highlights its pathogenic potential, particularly in immunocompromised individuals or those with underlying health issues. With a single replicon and a double membrane structure, Klebsiella pneumoniae SIKP063 exhibits typical traits of the Enterobacteriaceae family. Its ability to cause a diverse array of infections, including early onset neonatal sepsis and pyogenic liver abscesses, reflects its adaptability and persistence in various environments. Understanding the characteristics and pathogenic capabilities of Klebsiella pneumoniae strain SIKP063 is crucial for microbiologists and healthcare professionals, emphasizing the need for continued surveillance of its presence in clinical settings and the potential implications for public health. Its association with multiple hosts underscores the ecological interconnectedness and the potential for zoonotic transmission.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP063 68_NODE_78

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP063 68_NODE_78
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP063 68_NODE_78, whole genome

Gene Summary

Adenine Count

1153367 bp

Thymine Count

1149894 bp

Guanine Count

1533244 bp

Cytosine Count

1564470 bp

Genome Length

5400975 bp

Protein-coding Genes

4969 genes

Non-Coding Genes

355 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive1910048 - 1910060Not Available
IntegraseFAQ96_09540Not AvailableNegative1911078 - 191212139785.9
ExcisionaseFAQ96_09545Not AvailableNegative1912118 - 191245311844.3
Hypothetical proteinFAQ96_09550Not AvailableNegative1912455 - 19126738364.9
Dna methylaseFAQ96_09555Not AvailableNegative1912670 - 191319719503.9
Putative exonucleaseFAQ96_09560Not AvailableNegative1913226 - 191384923459.1
Recombination protein betFAQ96_09565Not AvailableNegative1913846 - 191459227465.6
Host nuclease inhibitorFAQ96_09570Not AvailableNegative1914609 - 191489310895.5
Hypothetical proteinFAQ96_09575Not AvailableNegative1914901 - 191587236776.4
Membrane carboxypeptidaseFAQ96_09580Not AvailableNegative1915953 - 19161597668.25

Displaying genes 1 – 10 of 5324 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total