Klebsiella pneumoniae strain SIKP054 59_NODE_89

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP054 59_NODE_89 is a gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph, indicating its ability to utilize organic compounds for energy in varying oxygen conditions. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in diverse arrangements, including chains, pairs, and singles. The optimal growth temperature for SIKP054 is 37°C, placing it in the mesophilic temperature range. This bacterium is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other Metazoa and Viridiplantae, suggesting a versatile ecological role. Klebsiella pneumoniae is known for its pathogenicity in humans, often causing serious health conditions such as bacteremia, urinary tract infections, pneumonia, and various abdominal infections. Its ability to cause a wide range of diseases, including neonatal sepsis and pyogenic liver abscesses, highlights its significance as a human pathogen. The strain is nonsporulating and possesses two membranes, a common feature among gram-negative bacteria. The diverse array of health effects associated with this strain underscores its importance in clinical microbiology and public health, particularly in understanding its role in hospital-acquired infections and antibiotic resistance. In summary, the ecological and biological insights into Klebsiella pneumoniae strain SIKP054 reveal its adaptability to various hosts and environments while posing significant health risks, making it a crucial subject for ongoing research in microbiology and infectious disease control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP054 59_NODE_89

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP054 59_NODE_89
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP054 59_NODE_89, whole genome

Gene Summary

Adenine Count

1176670 bp

Thymine Count

1182153 bp

Guanine Count

1586284 bp

Cytosine Count

1572168 bp

Genome Length

5517275 bp

Protein-coding Genes

5140 genes

Non-Coding Genes

309 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molecular chaperone dnakFAR07_24110Not AvailablePositive4863443 - 486535969112.7
molecular chaperone dnajFAR07_24115Not AvailablePositive4865447 - 486658041012.7
na+/h+ antiporter nhaaFAR07_24120Not AvailablePositive4866758 - 486793341259.3
transcriptional activator nharFAR07_24125Not AvailablePositive4867988 - 486888434036.1
30s ribosomal protein s20FAR07_24130Not AvailableNegative4869004 - 48692679670.91
bifunctional riboflavin kinase/fad synthetaseFAR07_24140Not AvailablePositive4869597 - 487053534373.8
isoleucine--trna ligaseFAR07_24145Not AvailablePositive4870579 - 4873395104531.0
lipoprotein signal peptidaseFAR07_24150Not AvailablePositive4873395 - 487389518326.6
fkbp-type peptidyl-prolyl cis-trans isomeraseFAR07_24155Not AvailablePositive4874011 - 487446016156.0
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseFAR07_24160Not AvailablePositive4874462 - 487541234449.1

Displaying genes 4771 – 4780 of 5449 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total