Klebsiella pneumoniae strain SIKP054 59_NODE_89

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP054 59_NODE_89 is a gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph, indicating its ability to utilize organic compounds for energy in varying oxygen conditions. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in diverse arrangements, including chains, pairs, and singles. The optimal growth temperature for SIKP054 is 37°C, placing it in the mesophilic temperature range. This bacterium is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other Metazoa and Viridiplantae, suggesting a versatile ecological role. Klebsiella pneumoniae is known for its pathogenicity in humans, often causing serious health conditions such as bacteremia, urinary tract infections, pneumonia, and various abdominal infections. Its ability to cause a wide range of diseases, including neonatal sepsis and pyogenic liver abscesses, highlights its significance as a human pathogen. The strain is nonsporulating and possesses two membranes, a common feature among gram-negative bacteria. The diverse array of health effects associated with this strain underscores its importance in clinical microbiology and public health, particularly in understanding its role in hospital-acquired infections and antibiotic resistance. In summary, the ecological and biological insights into Klebsiella pneumoniae strain SIKP054 reveal its adaptability to various hosts and environments while posing significant health risks, making it a crucial subject for ongoing research in microbiology and infectious disease control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP054 59_NODE_89

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP054 59_NODE_89
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP054 59_NODE_89, whole genome

Gene Summary

Adenine Count

1176670 bp

Thymine Count

1182153 bp

Guanine Count

1586284 bp

Cytosine Count

1572168 bp

Genome Length

5517275 bp

Protein-coding Genes

5140 genes

Non-Coding Genes

309 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane-stress sensor serine endopeptidase degsFAR07_14715Not AvailableNegative2981511 - 298256937125.8
serine endoprotease degqFAR07_14720Not AvailableNegative2982657 - 298402447273.3
duf1043 family proteinFAR07_14725Not AvailableNegative2984198 - 298459615046.8
cell division protein zapeFAR07_14730Not AvailablePositive2984787 - 298591442498.3
50s ribosomal protein l13FAR07_14735Not AvailablePositive2986180 - 298660816110.6
30s ribosomal protein s9FAR07_14740Not AvailablePositive2986624 - 298701614857.1
hypothetical proteinFAR07_14745Not AvailablePositive2987074 - 298735810729.8
stringent starvation protein aFAR07_14750Not AvailablePositive2987328 - 298796624191.2
clpxp protease specificity-enhancing factorFAR07_14755Not AvailablePositive2987970 - 298846417968.0
n-acetylmannosamine-6-phosphate 2-epimeraseFAR07_14760Not AvailablePositive2988589 - 298929324503.4

Displaying genes 3021 – 3030 of 5449 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total