Klebsiella pneumoniae strain SIKP092 100_NODE_92

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP092 (accession STAW00000000.1) is a Gram-negative, facultative anaerobic bacterium characterized by a rod shape and the presence of flagella, allowing for mobility. This strain is classified as a chemoheterotroph and is capable of thriving in host-associated habitats, exhibiting a mesophilic temperature range with an optimal growth temperature of 37°C. K. pneumoniae SIKP092 typically exists in various cell arrangements, including chains, pairs, and singles, and possesses a single replicon and a double membrane structure. It can be free-living and has been isolated from multiple hosts, including Homo sapiens, Gallus gallus, and other animals across the Metazoa and Viridiplantae kingdoms. This bacterium is notable for its pathogenicity in humans, being implicated in a range of health effects such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain has also been associated with severe conditions like sepsis, neonatal sepsis, and pyogenic liver abscesses, indicating its potential to cause significant morbidity. The ecological insight gleaned from K. pneumoniae SIKP092's diverse host associations suggests a complex interplay between this bacterium and various environments, highlighting its adaptability and potential role as an opportunistic pathogen in both human and animal health contexts. Understanding its pathogenic mechanisms and ecological relationships is crucial for developing effective treatments and prevention strategies against infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP092 100_NODE_92

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP092 100_NODE_92
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP092 100_NODE_92, whole genome

Gene Summary

Adenine Count

1213379 bp

Thymine Count

1222836 bp

Guanine Count

1633383 bp

Cytosine Count

1591166 bp

Genome Length

5660764 bp

Protein-coding Genes

5183 genes

Non-Coding Genes

403 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ethanolamine utilization ethanol dehydrogenase eutgFAQ98_08965Not AvailablePositive1748278 - 174946541412.4
ethanolamine utilization protein euthFAQ98_08970Not AvailablePositive1749665 - 175089743082.0
ethanolamine ammonia-lyase reactivating factor eutaFAQ98_08975Not AvailablePositive1750894 - 175229749249.8
ethanolamine ammonia-lyase subunit eutbFAQ98_08980Not AvailablePositive1752309 - 175367049512.1
ethanolamine ammonia-lyase subunit eutcFAQ98_08985Not AvailablePositive1753691 - 175459032117.7
ethanolamine utilization microcompartment protein eutlFAQ98_08990Not AvailablePositive1754600 - 175525922687.0
ethanolamine utilization microcompartment protein eutkFAQ98_08995Not AvailablePositive1755271 - 175575617061.7
hth-type transcriptional regulator eutrFAQ98_09000Not AvailablePositive1755802 - 175685440309.3
oxygen-dependent coproporphyrinogen oxidaseFAQ98_09005Not AvailableNegative1756898 - 175779734214.2
n-acetylmuramoyl-l-alanine amidase amiaFAQ98_09010Not AvailableNegative1757797 - 175866931370.8

Displaying genes 1981 – 1990 of 5586 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total