Klebsiella pneumoniae subsp. pneumoniae strain SIKP091

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP091 is a significant pathogenic bacterium primarily associated with pneumonia, including community-acquired pneumonia (CAP). This species is a Gram-negative, rod-shaped organism that exhibits a facultative anaerobic metabolism, allowing it to thrive in both oxygen-rich and low-oxygen environments. SIKP091 is chemoheterotrophic, utilizing organic compounds as its energy source. In terms of morphology, this strain can be observed in various arrangements, including chains, pairs, and singles. It possesses flagella, contributing to its mobility and enabling it to navigate its host-associated habitats effectively. The optimal growth temperature for SIKP091 is 37°C, which aligns with the human body temperature, suggesting its adaptation to host environments. The strain is mesophilic, indicating that it prefers moderate temperature ranges. Klebsiella pneumoniae subsp. pneumoniae has a single replicon and is characterized by a bi-layered membrane structure, which is typical of Gram-negative bacteria. Notably, this strain is nonsporulating, indicating that it does not form spores under adverse conditions. From a biological perspective, the free-living nature of SIKP091, combined with its pathogenic potential, underscores its ecological role as both a commensal and an opportunistic pathogen in human hosts. Its capability to thrive in diverse conditions reflects its adaptability, making it a notable concern in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP091

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP091
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP091

Gene Summary

Adenine Count

1245965 bp

Thymine Count

1246110 bp

Guanine Count

1632847 bp

Cytosine Count

1640353 bp

Genome Length

5765275 bp

Protein-coding Genes

5336 genes

Non-Coding Genes

280 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
mdr efflux pump acrab transcriptional activator robaFAR05_00490Not AvailableNegative90650 - 9151933330.1
protein creaFAR05_00495Not AvailablePositive91729 - 9220217154.8
two-component system response regulator crebFAR05_00500Not AvailablePositive92215 - 9290425776.4
two-component system sensor histidine kinase crecFAR05_00505Not AvailablePositive92904 - 9432852496.5
cell envelope integrity protein credFAR05_00510Not AvailablePositive94392 - 9574749936.9
two-component system response regulator arcaFAR05_00515Not AvailableNegative95810 - 9652627273.6
hypothetical proteinFAR05_00520Not AvailablePositive96622 - 967624887.07
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive96733 - 96829Not Available
trna/rrna methyltransferaseFAR05_00525Not AvailablePositive97159 - 9784525114.3
thr operon leader peptideFAR05_00530Not AvailablePositive98057 - 981252237.79

Displaying genes 351 – 360 of 5616 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total