Klebsiella pneumoniae subsp. pneumoniae strain SIKP091

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP091 is a significant pathogenic bacterium primarily associated with pneumonia, including community-acquired pneumonia (CAP). This species is a Gram-negative, rod-shaped organism that exhibits a facultative anaerobic metabolism, allowing it to thrive in both oxygen-rich and low-oxygen environments. SIKP091 is chemoheterotrophic, utilizing organic compounds as its energy source. In terms of morphology, this strain can be observed in various arrangements, including chains, pairs, and singles. It possesses flagella, contributing to its mobility and enabling it to navigate its host-associated habitats effectively. The optimal growth temperature for SIKP091 is 37°C, which aligns with the human body temperature, suggesting its adaptation to host environments. The strain is mesophilic, indicating that it prefers moderate temperature ranges. Klebsiella pneumoniae subsp. pneumoniae has a single replicon and is characterized by a bi-layered membrane structure, which is typical of Gram-negative bacteria. Notably, this strain is nonsporulating, indicating that it does not form spores under adverse conditions. From a biological perspective, the free-living nature of SIKP091, combined with its pathogenic potential, underscores its ecological role as both a commensal and an opportunistic pathogen in human hosts. Its capability to thrive in diverse conditions reflects its adaptability, making it a notable concern in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP091

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP091
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP091

Gene Summary

Adenine Count

1245965 bp

Thymine Count

1246110 bp

Guanine Count

1632847 bp

Cytosine Count

1640353 bp

Genome Length

5765275 bp

Protein-coding Genes

5336 genes

Non-Coding Genes

280 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
purine-nucleoside phosphorylaseFAR05_00435Not AvailablePositive78859 - 7957825946.4
lipoate--protein ligase lplaFAR05_00440Not AvailableNegative79659 - 8067537759.5
ytjb family periplasmic proteinFAR05_00445Not AvailableNegative80675 - 8132224073.3
phosphoserine phosphataseFAR05_00450Not AvailablePositive81427 - 8239835165.8
dna repair protein radaFAR05_00455Not AvailablePositive82408 - 8379049434.0
multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase nadrFAR05_00460Not AvailablePositive83812 - 8504447190.2
murein transglycosylaseFAR05_00470Not AvailablePositive87035 - 8897273145.6
trp operon repressorFAR05_00475Not AvailablePositive89061 - 8939012397.9
non-canonical purine ntp phosphataseFAR05_00480Not AvailableNegative89377 - 8989218359.6
phosphoglycerate mutase gpmbFAR05_00485Not AvailablePositive90006 - 9065323869.4

Displaying genes 341 – 350 of 5616 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total