Klebsiella pneumoniae strain SIKP086 94_NODE_92

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP086 94_NODE_92 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments. As a chemoheterotroph, it derives energy from organic compounds, and it exhibits facultative anaerobic characteristics, allowing it to grow in both aerobic and anaerobic conditions. This strain typically arranges itself in chains, pairs, or singles and possesses flagella, indicating motility. The optimal growth temperature for SIKP086 is 37°C, placing it in the mesophilic range. It contains one replicon and is characterized by a double membrane structure. Its biotic relationship is classified as free-living, although it is primarily associated with a wide range of hosts, including Homo sapiens, various domesticated animals, and some plant species. Klebsiella pneumoniae is known for its pathogenicity, particularly in humans, where it can lead to severe health complications such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It is also implicated in neonatal sepsis and other critical conditions like septicemia and liver abscesses. The ecological significance of Klebsiella pneumoniae strain SIKP086 lies in its adaptability to diverse environments and hosts. Its ability to cause infections across a broad spectrum of species highlights its potential impact on public health and veterinary medicine. Understanding the pathogenic mechanisms and environmental interactions of this strain is crucial for developing effective treatment strategies and managing its transmission in clinical and agricultural settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP086 94_NODE_92

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP086 94_NODE_92
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP086 94_NODE_92, whole genome

Gene Summary

Adenine Count

1184176 bp

Thymine Count

1180967 bp

Guanine Count

1585862 bp

Cytosine Count

1580117 bp

Genome Length

5531122 bp

Protein-coding Genes

5152 genes

Non-Coding Genes

359 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipoprotein-releasing abc transporter atp-binding protein loldFAQ80_06420Not AvailablePositive1326670 - 132737125577.0
lipoprotein-releasing abc transporter permease subunit loleFAQ80_06425Not AvailablePositive1327371 - 132861545093.6
n-acetylglucosamine kinaseFAQ80_06430Not AvailablePositive1328664 - 132957533113.6
nad-dependent protein deacylaseFAQ80_06435Not AvailablePositive1329590 - 133042031225.4
hypothetical proteinFAQ80_06440Not AvailablePositive1330511 - 133085512447.8
sugar-binding transcriptional regulatorFAQ80_06445Not AvailableNegative1330880 - 133184235254.3
triose-phosphate isomeraseFAQ80_06450Not AvailableNegative1331878 - 133267229100.0
4-hydroxythreonine-4-phosphate dehydrogenase pdxaFAQ80_06455Not AvailablePositive1332915 - 133392236537.3
four-carbon acid sugar kinase family proteinFAQ80_06460Not AvailablePositive1333958 - 133567661218.0
2-keto-3-deoxygluconate permeaseFAQ80_06465Not AvailablePositive1335769 - 133678835073.1

Displaying genes 1531 – 1540 of 5511 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total