Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74 is a Gram-negative, rod-shaped bacterium that exhibits a diverse cell arrangement, forming chains, pairs, or existing as singles. This strain is categorized as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, typically at an optimal temperature of 37°C, which falls within the mesophilic range. As a chemoheterotroph, SIKP080 derives its energy from organic compounds, making it dependent on other organisms for nutrients. It possesses flagella, demonstrating mobility, which may facilitate its dispersal and colonization within host environments. The strain has a biotic relationship characterized as free-living, indicating its capability to survive independently outside of a host organism. Klebsiella pneumoniae subsp. pneumoniae is known to be associated with significant human health concerns, particularly as a causative agent of pneumonia, including community-acquired pneumonia (CAP). The strain is nonsporulating, which suggests it does not produce spores, a feature that can influence its survival and transmission dynamics in various environments. With a single replicon and a double membrane structure, SIKP080 reflects the typical characteristics of Gram-negative bacteria, contributing to its physiological properties and interactions with host systems. Understanding these traits is crucial for developing strategies to manage infections caused by this bacterium, particularly in clinical settings where it poses a risk to vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP080 88_NODE_74

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74,

Gene Summary

Adenine Count

1158342 bp

Thymine Count

1161792 bp

Guanine Count

1556327 bp

Cytosine Count

1558714 bp

Genome Length

5435175 bp

Protein-coding Genes

5028 genes

Non-Coding Genes

357 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane integrity-associated transporter subunit pqicFAQ81_18965Not AvailableNegative3859536 - 386009920386.2
intermembrane transport protein pqibFAQ81_18970Not AvailableNegative3860099 - 386173660150.3
membrane integrity-associated transporter subunit pqiaFAQ81_18975Not AvailableNegative3861726 - 386299447157.2
abc transporter atp-binding proteinFAQ81_18980Not AvailableNegative3863009 - 386491671604.5
bifunctional 23s rrna (guanine(2069)-n(7))-methyltransferase rlmk/23s rrna (guanine(2445)-n(2))-methyltransferase rlmlFAQ81_18985Not AvailableNegative3864929 - 386703478915.6
mosc domain-containing proteinFAQ81_18990Not AvailablePositive3867134 - 386824340427.3
cell division protein zapcFAQ81_18995Not AvailableNegative3868240 - 386878220400.5
quinone-dependent dihydroorotate dehydrogenaseFAQ81_19000Not AvailableNegative3868952 - 386996236750.9
nadph-dependent fmn reductaseFAQ81_19005Not AvailablePositive3870212 - 387078721027.2
sulfonate abc transporter substrate-binding proteinFAQ81_19010Not AvailablePositive3870780 - 387174234274.1

Displaying genes 3921 – 3930 of 5385 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total