Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74 is a Gram-negative, rod-shaped bacterium that exhibits a diverse cell arrangement, forming chains, pairs, or existing as singles. This strain is categorized as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, typically at an optimal temperature of 37°C, which falls within the mesophilic range. As a chemoheterotroph, SIKP080 derives its energy from organic compounds, making it dependent on other organisms for nutrients. It possesses flagella, demonstrating mobility, which may facilitate its dispersal and colonization within host environments. The strain has a biotic relationship characterized as free-living, indicating its capability to survive independently outside of a host organism. Klebsiella pneumoniae subsp. pneumoniae is known to be associated with significant human health concerns, particularly as a causative agent of pneumonia, including community-acquired pneumonia (CAP). The strain is nonsporulating, which suggests it does not produce spores, a feature that can influence its survival and transmission dynamics in various environments. With a single replicon and a double membrane structure, SIKP080 reflects the typical characteristics of Gram-negative bacteria, contributing to its physiological properties and interactions with host systems. Understanding these traits is crucial for developing strategies to manage infections caused by this bacterium, particularly in clinical settings where it poses a risk to vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP080 88_NODE_74

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP080 88_NODE_74,

Gene Summary

Adenine Count

1158342 bp

Thymine Count

1161792 bp

Guanine Count

1556327 bp

Cytosine Count

1558714 bp

Genome Length

5435175 bp

Protein-coding Genes

5028 genes

Non-Coding Genes

357 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetolactate synthase 3 large subunitFAQ81_18400Not AvailableNegative3743135 - 374485963075.2
hypothetical proteinFAQ81_18405Not AvailablePositive3744858 - 37450497238.95
transcriptional regulator leuoFAQ81_18410Not AvailableNegative3745254 - 374622236534.1
leu operon leader peptideFAQ81_18415Not AvailablePositive3746836 - 37469223191.1
2-isopropylmalate synthaseFAQ81_18420Not AvailablePositive3747018 - 374858957517.4
3-isopropylmalate dehydrogenaseFAQ81_18425Not AvailablePositive3748589 - 374968039504.3
3-isopropylmalate dehydratase large subunitFAQ81_18430Not AvailablePositive3749683 - 375108349831.6
3-isopropylmalate dehydratase small subunitFAQ81_18435Not AvailablePositive3751094 - 375169922582.7
fad-dependent oxidoreductaseFAQ81_18440Not AvailablePositive3752095 - 375412874853.3
shikimate dehydrogenaseFAQ81_18445Not AvailablePositive3754140 - 375500331512.2

Displaying genes 3811 – 3820 of 5385 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total