Klebsiella pneumoniae strain SIKP070 76_NODE_99

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP070 76_NODE_99 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophy for energy. This strain is characterized by its ability to form chains, pairs, and single cells, demonstrating a versatile cell arrangement. It is motile and possesses flagella, which may contribute to its capacity to colonize various hosts. The optimal growth temperature for SIKP070 is 37°C, placing it in the mesophilic range, suitable for thriving in warm-blooded hosts. Its biotic relationships indicate it is free-living while also having a significant host range that includes Homo sapiens, various birds, mammals, and even some plants. This diverse array of hosts highlights its ecological adaptability and potential for cross-species transmission. Clinically, Klebsiella pneumoniae is known for its pathogenicity in humans, being associated with a variety of severe infections, including bacteremia, pneumonia, urinary tract infections, and intra-abdominal infections. The extensive health effects listed underline its role as a significant opportunistic pathogen, particularly in immunocompromised patients. The presence of a single replicon and double membranes suggests a typical structure for Gram-negative bacteria, which may impact its interactions with the host's immune system. Understanding the traits of SIKP070 contributes to the broader knowledge of Klebsiella pneumoniae and its implications in human health, particularly in the context of antibiotic resistance and infection control measures. The ecological versatility of this strain emphasizes the importance of monitoring its transmission dynamics within various environments and host species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP070 76_NODE_99

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP070 76_NODE_99
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP070 76_NODE_99, whole genome

Gene Summary

Adenine Count

1181343 bp

Thymine Count

1178540 bp

Guanine Count

1569288 bp

Cytosine Count

1590711 bp

Genome Length

5519882 bp

Protein-coding Genes

5109 genes

Non-Coding Genes

340 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinFAQ83_12585Not AvailablePositive2565313 - 256577417348.8
Hypothetical proteinFAQ83_12590Not AvailablePositive2565836 - 25660186719.95
Putative antirepressorFAQ83_12595Not AvailablePositive2566012 - 25662248639.21
Putative phage o family proteinFAQ83_12600Not AvailablePositive2566181 - 256709534844.9
Methyl-directed repair dna adenine methylaseFAQ83_12605Not AvailablePositive2567092 - 256790130231.2
Holiday-junction resolvaseFAQ83_12610Not AvailablePositive2567911 - 256828814303.4
Hypothetical proteinFAQ83_12615Not AvailablePositive2568301 - 256928137019.8
duf1133 family proteinFAQ83_12620Not AvailablePositive2569295 - 256987321795.6
hypothetical proteinFAQ83_12625Not AvailablePositive2569980 - 257058522752.7
Putative holinFAQ83_12630Not AvailablePositive2570825 - 257121112871.6

Displaying genes 41 – 50 of 5449 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total