Klebsiella pneumoniae strain SIKP066 71_NODE_90

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP066 71_NODE_90 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is distinguished by its ability to form chains, pairs, or exist as single cells and possesses flagella, indicating motility. It has a mesophilic growth profile, with an optimal temperature of 37°C. SIKP066 has a single replicon and a double membrane structure typical of Gram-negative bacteria. Its habitat is primarily host-associated, indicating a symbiotic or pathogenic relationship with various hosts, including Homo sapiens, Gallus gallus, and several other vertebrates and plants. This strain is known for its pathogenic effects in humans, causing a range of serious health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The wide array of hosts it affects suggests that Klebsiella pneumoniae strain SIKP066 may have adapted to thrive in diverse environments, potentially enhancing its survival and pathogenicity across different biological systems. Its ability to infect both mammals and other organisms underscores its ecological versatility and may reflect the complex interactions within host-associated microbiomes. This adaptability poses significant public health challenges, highlighting the importance of monitoring Klebsiella pneumoniae strains in clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP066 71_NODE_90

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP066 71_NODE_90
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP066 71_NODE_90, whole genome

Gene Summary

Adenine Count

1173481 bp

Thymine Count

1183069 bp

Guanine Count

1582724 bp

Cytosine Count

1571518 bp

Genome Length

5510792 bp

Protein-coding Genes

5129 genes

Non-Coding Genes

312 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
threonine ammonia-lyase, biosyntheticFAO21_19465Not AvailablePositive3981188 - 398273256222.6
hth-type transcriptional activator ilvyFAO21_19470Not AvailableNegative3982729 - 398361933029.0
ketol-acid reductoisomeraseFAO21_19475Not AvailablePositive3983772 - 398524753955.0
peptidylprolyl isomerase cFAO21_19480Not AvailableNegative3985451 - 398573210276.7
peptidyl-prolyl cis-trans isomeraseFAO21_19485Not AvailableNegative3985784 - 398606510306.7
dna helicase repFAO21_19490Not AvailablePositive3986178 - 398819976885.4
duf554 domain-containing proteinFAO21_19495Not AvailableNegative3988204 - 398892625585.4
amidohydrolaseFAO21_19500Not AvailableNegative3988989 - 398998737523.7
lysr family transcriptional regulatorFAO21_19505Not AvailableNegative3990118 - 399104434814.1
guanosine-5'-triphosphate,3'-diphosphate diphosphataseFAO21_19510Not AvailableNegative3991064 - 399256355013.8

Displaying genes 3981 – 3990 of 5441 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total