Klebsiella pneumoniae subsp. pneumoniae strain SIKP103

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP103 is a Gram-negative, rod-shaped bacterium that exhibits a range of notable traits. It is classified as a chemoheterotroph, indicating that it derives energy from organic compounds. This strain is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments. Its typical habitat is host-associated, which aligns with its association with community-acquired pneumonia (CAP), a significant health concern. The bacterium exhibits a unique cell arrangement, appearing in chains, pairs, and singles, and possesses flagella, contributing to its mobility. SIKP103 has a mesophilic temperature range, with an optimal growth temperature of 37°C, which corresponds to the human body temperature, further emphasizing its role as a pathogen in humans. In terms of cellular structure, SIKP103 has two membranes and a single replicon, characteristics common to Gram-negative bacteria. It is nonsporulating, which means it does not form spores under adverse conditions. The biotic relationship of Klebsiella pneumoniae subsp. pneumoniae strain SIKP103 is categorized as free-living, yet its pathogenic potential in humans poses substantial health risks, particularly in causing pneumonia. Understanding the ecological and biological traits of this strain is crucial for developing strategies to manage its impact on human health, especially in community settings where infections can quickly spread. The traits of SIKP103 highlight the delicate balance between microbial existence and pathogenicity within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP103

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP103
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP103

Gene Summary

Adenine Count

1154373 bp

Thymine Count

1150298 bp

Guanine Count

1557737 bp

Cytosine Count

1540267 bp

Genome Length

5402675 bp

Protein-coding Genes

4978 genes

Non-Coding Genes

346 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lps assembly protein lptdFAO11_20220Not AvailablePositive4066349 - 406869788493.1
peptidylprolyl isomerase suraFAO11_20225Not AvailablePositive4068752 - 407003847065.3
4-hydroxythreonine-4-phosphate dehydrogenase pdxaFAO11_20230Not AvailablePositive4070044 - 407103335081.9
16s rrna (adenine(1518)-n(6)/adenine(1519)-n(6))- dimethyltransferase rsmaFAO11_20235Not AvailablePositive4071030 - 407185130584.2
co2+/mg2+ efflux protein apagFAO11_20240Not AvailablePositive4071854 - 407223113999.7
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)FAO11_20245Not AvailablePositive4072236 - 407308431599.5
hypothetical proteinFAO11_20250Not AvailableNegative4073037 - 40732407421.87
hypothetical proteinFAO11_20255Not AvailablePositive4073230 - 40734759031.79
d-glycero-beta-d-manno-heptose 1,7-bisphosphate 7-phosphataseFAO11_20260Not AvailableNegative4073772 - 407433820949.9
methionine abc transporter atp-binding protein metnFAO11_20265Not AvailablePositive4074527 - 407555837635.5

Displaying genes 4081 – 4090 of 5324 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total