Klebsiella pneumoniae subsp. pneumoniae strain SIKP103

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP103 is a Gram-negative, rod-shaped bacterium that exhibits a range of notable traits. It is classified as a chemoheterotroph, indicating that it derives energy from organic compounds. This strain is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments. Its typical habitat is host-associated, which aligns with its association with community-acquired pneumonia (CAP), a significant health concern. The bacterium exhibits a unique cell arrangement, appearing in chains, pairs, and singles, and possesses flagella, contributing to its mobility. SIKP103 has a mesophilic temperature range, with an optimal growth temperature of 37°C, which corresponds to the human body temperature, further emphasizing its role as a pathogen in humans. In terms of cellular structure, SIKP103 has two membranes and a single replicon, characteristics common to Gram-negative bacteria. It is nonsporulating, which means it does not form spores under adverse conditions. The biotic relationship of Klebsiella pneumoniae subsp. pneumoniae strain SIKP103 is categorized as free-living, yet its pathogenic potential in humans poses substantial health risks, particularly in causing pneumonia. Understanding the ecological and biological traits of this strain is crucial for developing strategies to manage its impact on human health, especially in community settings where infections can quickly spread. The traits of SIKP103 highlight the delicate balance between microbial existence and pathogenicity within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP103

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP103
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP103

Gene Summary

Adenine Count

1154373 bp

Thymine Count

1150298 bp

Guanine Count

1557737 bp

Cytosine Count

1540267 bp

Genome Length

5402675 bp

Protein-coding Genes

4978 genes

Non-Coding Genes

346 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ribdFAO11_14080Not AvailablePositive2844118 - 284522140122.4
6,7-dimethyl-8-ribityllumazine synthaseFAO11_14085Not AvailablePositive2845309 - 284577916157.4
transcription antitermination factor nusbFAO11_14090Not AvailablePositive2845799 - 284621815764.9
thiamine-phosphate kinaseFAO11_14095Not AvailablePositive2846290 - 284726134743.6
phosphatidylglycerophosphatase aFAO11_14100Not AvailablePositive2847254 - 284775718951.5
aldo/keto reductaseFAO11_14105Not AvailableNegative2847803 - 284877736156.7
1-deoxy-d-xylulose-5-phosphate synthaseFAO11_14110Not AvailableNegative2848838 - 285070067350.3
(2e,6e)-farnesyl diphosphate synthaseFAO11_14115Not AvailableNegative2850719 - 285161832230.6
exodeoxyribonuclease vii small subunitFAO11_14120Not AvailableNegative2851619 - 28518618825.22
trna 4-thiouridine(8) synthase thiiFAO11_14125Not AvailablePositive2852043 - 285349154720.0

Displaying genes 2981 – 2990 of 5324 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total