Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is a Gram-negative, rod-shaped bacterium that exhibits a variety of notable traits. This strain is a chemoheterotroph, deriving its energy from organic compounds, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. SIKP100 typically exists in chains, pairs, or as single cells, showcasing a flexible arrangement that may assist in its adaptation to different habitats. The strain's optimal growth temperature is 37°C, placing it within the mesophilic range, which is conducive to its survival in human hosts. SIKP100 is motile, equipped with flagella, which may enhance its ability to colonize and spread within host environments. Importantly, it has a single replicon and is characterized by two membranes. From a health perspective, Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is associated with pneumonia, specifically community-acquired pneumonia (CAP), highlighting its significance as a human pathogen. Its nonsporulating nature suggests that it relies on other survival mechanisms in fluctuating conditions. Ecologically, SIKP100 exhibits a free-living biotic relationship, indicating that it can survive independently of a host under certain conditions. This adaptability may contribute to its role in environmental reservoirs and its potential for transmission, emphasizing the need for continued monitoring and research into its pathogenicity and ecological dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gene Summary

Adenine Count

1174613 bp

Thymine Count

1177863 bp

Guanine Count

1576671 bp

Cytosine Count

1563550 bp

Genome Length

5492697 bp

Protein-coding Genes

5177 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
5-deoxy-glucuronate isomeraseFAO13_23595Not AvailablePositive4794660 - 479546930427.7
cupin domain-containing proteinFAO13_23600Not AvailablePositive4796239 - 479736042480.1
gnat family n-acetyltransferaseFAO13_23605Not AvailableNegative4797408 - 479794119811.8
duf1778 domain-containing proteinFAO13_23610Not AvailableNegative4797952 - 47982189997.03
heavy metal sensor histidine kinaseFAO13_23615Not AvailableNegative4798321 - 479975453767.1
copper response regulator transcription factor cusrFAO13_23620Not AvailableNegative4799744 - 480042725292.9
cation transporterFAO13_23625Not AvailablePositive4800492 - 48006325247.3
efflux transporter outer membrane subunitFAO13_23630Not AvailablePositive4800599 - 480198450642.8
copper-binding proteinFAO13_23635Not AvailablePositive4802002 - 480234612305.0
efflux rnd transporter periplasmic adaptor subunitFAO13_23640Not AvailablePositive4802392 - 480365445798.1

Displaying genes 4661 – 4670 of 5357 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total