Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is a Gram-negative, rod-shaped bacterium that exhibits a variety of notable traits. This strain is a chemoheterotroph, deriving its energy from organic compounds, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. SIKP100 typically exists in chains, pairs, or as single cells, showcasing a flexible arrangement that may assist in its adaptation to different habitats. The strain's optimal growth temperature is 37°C, placing it within the mesophilic range, which is conducive to its survival in human hosts. SIKP100 is motile, equipped with flagella, which may enhance its ability to colonize and spread within host environments. Importantly, it has a single replicon and is characterized by two membranes. From a health perspective, Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is associated with pneumonia, specifically community-acquired pneumonia (CAP), highlighting its significance as a human pathogen. Its nonsporulating nature suggests that it relies on other survival mechanisms in fluctuating conditions. Ecologically, SIKP100 exhibits a free-living biotic relationship, indicating that it can survive independently of a host under certain conditions. This adaptability may contribute to its role in environmental reservoirs and its potential for transmission, emphasizing the need for continued monitoring and research into its pathogenicity and ecological dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gene Summary

Adenine Count

1174613 bp

Thymine Count

1177863 bp

Guanine Count

1576671 bp

Cytosine Count

1563550 bp

Genome Length

5492697 bp

Protein-coding Genes

5177 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alpa family phage regulatory proteinFAO13_18935Not AvailablePositive3901450 - 39016357072.71
hypothetical proteinFAO13_18945Not AvailableNegative3902708 - 39029449253.51
hypothetical proteinFAO13_18950Not AvailablePositive3903567 - 390388412553.9
abc-2 transporter permeaseFAO13_18955Not AvailableNegative3903925 - 390504941123.5
atp-binding cassette domain-containing proteinFAO13_18960Not AvailableNegative3905049 - 3907793100910.0
hlyd family efflux transporter periplasmic adaptor subunitFAO13_18965Not AvailableNegative3907790 - 390885738674.6
diguanylate cyclaseFAO13_18970Not AvailablePositive3909260 - 391065452714.3
tryptophan--trna ligaseFAO13_18975Not AvailableNegative3910703 - 391171037051.7
autoinducer 2 abc transporter substrate-binding proteinFAO13_18980Not AvailablePositive3912212 - 391319835768.2
sugar abc transporter atp-binding proteinFAO13_18985Not AvailablePositive3913249 - 391473354046.7

Displaying genes 3761 – 3770 of 5357 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total