Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is a Gram-negative, rod-shaped bacterium that exhibits a variety of notable traits. This strain is a chemoheterotroph, deriving its energy from organic compounds, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. SIKP100 typically exists in chains, pairs, or as single cells, showcasing a flexible arrangement that may assist in its adaptation to different habitats. The strain's optimal growth temperature is 37°C, placing it within the mesophilic range, which is conducive to its survival in human hosts. SIKP100 is motile, equipped with flagella, which may enhance its ability to colonize and spread within host environments. Importantly, it has a single replicon and is characterized by two membranes. From a health perspective, Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is associated with pneumonia, specifically community-acquired pneumonia (CAP), highlighting its significance as a human pathogen. Its nonsporulating nature suggests that it relies on other survival mechanisms in fluctuating conditions. Ecologically, SIKP100 exhibits a free-living biotic relationship, indicating that it can survive independently of a host under certain conditions. This adaptability may contribute to its role in environmental reservoirs and its potential for transmission, emphasizing the need for continued monitoring and research into its pathogenicity and ecological dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gene Summary

Adenine Count

1174613 bp

Thymine Count

1177863 bp

Guanine Count

1576671 bp

Cytosine Count

1563550 bp

Genome Length

5492697 bp

Protein-coding Genes

5177 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-binding transcriptional activator mhprFAO13_14400Not AvailablePositive2971973 - 297278530602.9
hypothetical proteinFAO13_14405Not AvailablePositive2972877 - 297393539331.4
iron abc transporter permeaseFAO13_14410Not AvailablePositive2973925 - 297493235109.2
abc transporter atp-binding proteinFAO13_14415Not AvailablePositive2974929 - 297567826905.5
molybdate abc transporter substrate-binding proteinFAO13_14420Not AvailableNegative2975662 - 297640526430.6
shikimate dehydrogenaseFAO13_14425Not AvailableNegative2976462 - 297729830013.6
mfs transporterFAO13_14430Not AvailableNegative2977314 - 297863647773.2
sugar phosphate isomerase/epimerase and 4-hydroxyphenylpyruvate domain-containing proteinFAO13_14435Not AvailableNegative2978708 - 298056168694.6
tetr family transcriptional regulatorFAO13_14440Not AvailablePositive2980688 - 298132624236.2
fumarate hydratase fumdFAO13_14445Not AvailableNegative2981344 - 29815567825.69

Displaying genes 2881 – 2890 of 5357 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total