Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is a Gram-negative, rod-shaped bacterium that exhibits a variety of notable traits. This strain is a chemoheterotroph, deriving its energy from organic compounds, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. SIKP100 typically exists in chains, pairs, or as single cells, showcasing a flexible arrangement that may assist in its adaptation to different habitats. The strain's optimal growth temperature is 37°C, placing it within the mesophilic range, which is conducive to its survival in human hosts. SIKP100 is motile, equipped with flagella, which may enhance its ability to colonize and spread within host environments. Importantly, it has a single replicon and is characterized by two membranes. From a health perspective, Klebsiella pneumoniae subsp. pneumoniae strain SIKP100 is associated with pneumonia, specifically community-acquired pneumonia (CAP), highlighting its significance as a human pathogen. Its nonsporulating nature suggests that it relies on other survival mechanisms in fluctuating conditions. Ecologically, SIKP100 exhibits a free-living biotic relationship, indicating that it can survive independently of a host under certain conditions. This adaptability may contribute to its role in environmental reservoirs and its potential for transmission, emphasizing the need for continued monitoring and research into its pathogenicity and ecological dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP100

Gene Summary

Adenine Count

1174613 bp

Thymine Count

1177863 bp

Guanine Count

1576671 bp

Cytosine Count

1563550 bp

Genome Length

5492697 bp

Protein-coding Genes

5177 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug efflux mfs transporterFAO13_12865Not AvailablePositive2660067 - 266126943341.5
duf4440 domain-containing proteinFAO13_12870Not AvailablePositive2661266 - 266164314213.8
rna polymerase sigma factor rposFAO13_12875Not AvailableNegative2661696 - 266268837948.0
murein hydrolase activator nlpdFAO13_12880Not AvailableNegative2662846 - 266398239331.1
protein-l-isoaspartate(d-aspartate) o-methyltransferaseFAO13_12885Not AvailableNegative2664108 - 266473423407.3
5'/3'-nucleotidase sureFAO13_12890Not AvailableNegative2664728 - 266548927366.5
trna pseudouridine(13) synthase trudFAO13_12895Not AvailableNegative2665470 - 266651939104.6
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseFAO13_12900Not AvailableNegative2666516 - 266699516955.6
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferaseFAO13_12905Not AvailableNegative2666995 - 266770525659.8
cell division protein ftsbFAO13_12910Not AvailableNegative2667725 - 266804211952.1

Displaying genes 2581 – 2590 of 5357 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total