Klebsiella pneumoniae subsp. pneumoniae strain SIKP098

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP098 is a notable Gram-negative bacterium primarily recognized for its role in causing pneumonia, particularly community-acquired pneumonia (CAP). This strain is a chemoheterotroph, meaning it derives its energy from organic compounds, and it has a mesophilic temperature range with an optimal growth temperature of 37°C. In terms of cellular structure, SIKP098 typically arranges itself in chains, pairs, or as single cells. It has a rod shape and possesses flagella, which contribute to its mobility. The strain has a dual-membrane system, characteristic of Gram-negative bacteria, and contains a single replicon, indicating a streamlined genomic organization. Klebsiella pneumoniae subsp. pneumoniae strain SIKP098 is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This adaptability enhances its survival and proliferation in various host-associated habitats. The ecological role of this strain can be seen in its free-living biotic relationship, suggesting it can exist independently while also being associated with hosts. Its pathogenic potential, particularly in causing CAP, underscores the importance of understanding its environmental interactions and adaptations. Such insights can inform public health strategies aimed at preventing and managing infections caused by this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP098

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP098
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP098

Gene Summary

Adenine Count

1184358 bp

Thymine Count

1198921 bp

Guanine Count

1604245 bp

Cytosine Count

1579103 bp

Genome Length

5566627 bp

Protein-coding Genes

5104 genes

Non-Coding Genes

396 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
metal/formaldehyde-sensitive transcriptional repressorFAO29_01355Not AvailablePositive256943 - 25721810136.3
s-(hydroxymethyl)glutathione dehydrogenase/class iii alcohol dehydrogenaseFAO29_01360Not AvailablePositive257243 - 25836139272.3
membrane-bound pqq-dependent dehydrogenase, glucose/quinate/shikimate familyFAO29_01365Not AvailableNegative258431 - 26080385037.3
lysr family transcriptional regulatorFAO29_01370Not AvailableNegative261104 - 26202733166.7
protocatechuate 3,4-dioxygenase subunit alphaFAO29_01375Not AvailableNegative262205 - 26282523121.3
protocatechuate 3,4-dioxygenase subunit betaFAO29_01380Not AvailableNegative262822 - 26356227893.2
voc family proteinFAO29_01385Not AvailablePositive263802 - 26514550718.3
carboxylesterase/lipase family proteinFAO29_01390Not AvailablePositive265187 - 26669255119.1
nad(p)-dependent alcohol dehydrogenaseFAO29_01395Not AvailableNegative266739 - 26782737553.7
glucan biosynthesis proteinFAO29_01400Not AvailablePositive268265 - 26992062761.2

Displaying genes 631 – 640 of 5500 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total