Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102 is a Gram-negative, rod-shaped bacterium known for its involvement in community-acquired pneumonia (CAP). This organism is classified as a chemoheterotroph, indicating that it derives its energy from organic compounds. SIKP001 exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. In terms of cellular arrangement, SIKP001 can be found in chains, pairs, or as single cells. Its mobility is facilitated by the presence of flagella, which contribute to its ability to navigate through various environments. The strain is mesophilic, with an optimal growth temperature of 37°C, which is consistent with the typical body temperature of humans, its primary host. Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 possesses a single replicon and is characterized by a double membrane structure, a common feature among Gram-negative bacteria. This strain does not undergo sporulation, indicating a reliance on other survival strategies in its host-associated habitat. The free-living nature of SIKP001 suggests that it can exist independently of a host, although it is primarily recognized for its pathogenic potential in humans. Its association with pneumonia highlights the ecological role of this bacterium in human health, particularly in respiratory infections. Understanding the characteristics of SIKP001 can aid in the development of targeted treatments and prevention strategies against Klebsiella-related infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP001 1_NODE_102

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102,

Gene Summary

Adenine Count

1179618 bp

Thymine Count

1175137 bp

Guanine Count

1566219 bp

Cytosine Count

1574717 bp

Genome Length

5495691 bp

Protein-coding Genes

5186 genes

Non-Coding Genes

173 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
response regulator transcription factorFAN83_03510Not AvailablePositive750351 - 75108828681.6
glucokinaseFAN83_03515Not AvailableNegative751142 - 75210734423.6
ion channel proteinFAN83_03520Not AvailablePositive752371 - 75360642668.3
indolepyruvate decarboxylaseFAN83_03525Not AvailableNegative753603 - 75526459991.9
l-glyceraldehyde 3-phosphate reductaseFAN83_03530Not AvailablePositive755445 - 75643737042.4
duf2502 domain-containing proteinFAN83_03535Not AvailablePositive756568 - 75692713950.0
mn(2+) uptake nramp transporter mnthFAN83_03540Not AvailableNegative756985 - 75822644211.4
nucleoside permease nupcFAN83_03545Not AvailablePositive758573 - 75977543583.6
eal domain-containing proteinFAN83_03550Not AvailableNegative759824 - 76199582180.5
Trna-alaNot AvailableNot AvailablePositive762205 - 762280Not Available

Displaying genes 811 – 820 of 5359 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total