Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102 is a Gram-negative, rod-shaped bacterium known for its involvement in community-acquired pneumonia (CAP). This organism is classified as a chemoheterotroph, indicating that it derives its energy from organic compounds. SIKP001 exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. In terms of cellular arrangement, SIKP001 can be found in chains, pairs, or as single cells. Its mobility is facilitated by the presence of flagella, which contribute to its ability to navigate through various environments. The strain is mesophilic, with an optimal growth temperature of 37°C, which is consistent with the typical body temperature of humans, its primary host. Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 possesses a single replicon and is characterized by a double membrane structure, a common feature among Gram-negative bacteria. This strain does not undergo sporulation, indicating a reliance on other survival strategies in its host-associated habitat. The free-living nature of SIKP001 suggests that it can exist independently of a host, although it is primarily recognized for its pathogenic potential in humans. Its association with pneumonia highlights the ecological role of this bacterium in human health, particularly in respiratory infections. Understanding the characteristics of SIKP001 can aid in the development of targeted treatments and prevention strategies against Klebsiella-related infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP001 1_NODE_102

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102,

Gene Summary

Adenine Count

1179618 bp

Thymine Count

1175137 bp

Guanine Count

1566219 bp

Cytosine Count

1574717 bp

Genome Length

5495691 bp

Protein-coding Genes

5186 genes

Non-Coding Genes

173 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multifunctional cca addition/repair proteinFAN83_11250Not AvailableNegative2330932 - 233217346016.4
sh3 domain-containing proteinFAN83_11255Not AvailableNegative2332235 - 233285523098.7
inorganic triphosphataseFAN83_11260Not AvailablePositive2333070 - 233436848329.8
bifunctionalFAN83_11265Not AvailablePositive2334392 - 2337226107369.0
bifunctional d-glycero-beta-d-manno-heptose-7-phosphate kinase/d-glycero-beta-d-manno-heptose 1-phosphate adenylyltransferase hldeFAN83_11270Not AvailablePositive2337285 - 233871851139.6
cell surface composition regulator glgsFAN83_11275Not AvailablePositive2338937 - 23391347741.05
accessory factor ubik family proteinFAN83_11280Not AvailableNegative2339170 - 233944210447.5
3,4-dihydroxy-2-butanone-4-phosphate synthaseFAN83_11285Not AvailablePositive2339820 - 234047323447.9
zinc transporter zuptFAN83_11290Not AvailableNegative2340535 - 234130526336.3
4,5-dopa dioxygenase extradiolFAN83_11295Not AvailablePositive2341492 - 234228328989.8

Displaying genes 2271 – 2280 of 5359 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total