Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102 is a Gram-negative, rod-shaped bacterium known for its involvement in community-acquired pneumonia (CAP). This organism is classified as a chemoheterotroph, indicating that it derives its energy from organic compounds. SIKP001 exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. In terms of cellular arrangement, SIKP001 can be found in chains, pairs, or as single cells. Its mobility is facilitated by the presence of flagella, which contribute to its ability to navigate through various environments. The strain is mesophilic, with an optimal growth temperature of 37°C, which is consistent with the typical body temperature of humans, its primary host. Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 possesses a single replicon and is characterized by a double membrane structure, a common feature among Gram-negative bacteria. This strain does not undergo sporulation, indicating a reliance on other survival strategies in its host-associated habitat. The free-living nature of SIKP001 suggests that it can exist independently of a host, although it is primarily recognized for its pathogenic potential in humans. Its association with pneumonia highlights the ecological role of this bacterium in human health, particularly in respiratory infections. Understanding the characteristics of SIKP001 can aid in the development of targeted treatments and prevention strategies against Klebsiella-related infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP001 1_NODE_102

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP001 1_NODE_102,

Gene Summary

Adenine Count

1179618 bp

Thymine Count

1175137 bp

Guanine Count

1566219 bp

Cytosine Count

1574717 bp

Genome Length

5495691 bp

Protein-coding Genes

5186 genes

Non-Coding Genes

173 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug efflux mfs transporterFAN83_05860Not AvailableNegative1231334 - 123253343015.0
extensin family proteinFAN83_05865Not AvailableNegative1232703 - 123338624930.9
d-alanine--d-alanine ligaseFAN83_05870Not AvailablePositive1233486 - 123458339447.4
duf2754 family proteinFAN83_05875Not AvailableNegative1234616 - 12348197714.49
duf2755 family proteinFAN83_05880Not AvailablePositive1235072 - 123537410997.9
duf1615 domain-containing proteinFAN83_05885Not AvailableNegative1235371 - 123647740781.9
peptide antibiotic transporter sbmaFAN83_05890Not AvailableNegative1236496 - 123771646738.4
isochorismatase family proteinFAN83_05895Not AvailableNegative1237834 - 123836719395.1
d-alanyl-d-alanine- carboxypeptidase/endopeptidase amphFAN83_05900Not AvailablePositive1238565 - 123972541998.4
porphobilinogen synthaseFAN83_05905Not AvailablePositive1239832 - 124080635457.5

Displaying genes 1271 – 1280 of 5359 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total