Klebsiella pneumoniae strain SIKP028 29_NODE_98

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP028 29_NODE_98 is a Gram-negative bacterium with a rod shape and is classified as a facultative anaerobe, indicating its ability to survive in both aerobic and anaerobic environments. This strain is a chemoheterotroph, sourcing its energy from organic compounds, and is characterized by its motility attributed to the presence of flagella. The optimal growth temperature for this strain is 37°C, positioning it within a mesophilic temperature range. In terms of cellular arrangement, SIKP028 can be found in chains, pairs, and singles, and it has a unique structure comprising two membranes and a single replicon. Its ecological role is described as free-living, yet it is also host-associated, suggesting a versatile lifestyle that allows it to thrive in various environments, including those associated with numerous hosts such as Homo sapiens, Gallus gallus, and various other animals. Klebsiella pneumoniae is known for its pathogenicity in humans, being linked to a wide array of health complications. These include bacteremia, urinary tract infections, pneumonia, and septicemia, among others. The strain's ability to cause such diverse infections highlights its clinical significance and the importance of understanding its biology and ecology for public health. The presence of this pathogen across multiple hosts suggests a potential for zoonotic transmission, emphasizing the interconnectedness of human and animal health in the context of infectious disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP028 29_NODE_98

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP028 29_NODE_98
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP028 29_NODE_98, whole genome

Gene Summary

Adenine Count

1185720 bp

Thymine Count

1199192 bp

Guanine Count

1610290 bp

Cytosine Count

1575934 bp

Genome Length

5571136 bp

Protein-coding Genes

5196 genes

Non-Coding Genes

339 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc-f family atp-binding cassette domain-containing proteinFAN76_08235Not AvailablePositive1666791 - 166841059004.6
rna chaperone/antiterminator cspaFAN76_08240Not AvailableNegative1668509 - 16687217403.66
hth-type transcriptional regulatorFAN76_08245Not AvailableNegative1668974 - 166926411184.5
mfs transporterFAN76_08250Not AvailableNegative1669510 - 167086548055.6
hypothetical proteinFAN76_08255Not AvailablePositive1671169 - 16713607537.51
duf3053 domain-containing proteinFAN76_08260Not AvailablePositive1671306 - 167201625531.4
glyoxylate/hydroxypyruvate reductase ghrbFAN76_08265Not AvailableNegative1672125 - 167309635434.6
mfs transporterFAN76_08270Not AvailableNegative1673121 - 167440146839.7
sugar kinaseFAN76_08275Not AvailableNegative1674506 - 167544133146.5
sugar phosphate isomerase/epimeraseFAN76_08280Not AvailableNegative1675445 - 167619427278.6

Displaying genes 1841 – 1850 of 5535 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total