Klebsiella pneumoniae strain SIKP008 9_NODE_96

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP008 9_NODE_96 is a gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain is capable of existing in various arrangements, including chains, pairs, and singles. It possesses flagella, which grants it mobility, and thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. SIKP008 is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various Metazoa, suggesting a broad ecological niche. Its presence in both animals and plants, including species such as Danio rerio and Viridiplantae, highlights its potential role in different biological contexts. This strain is notable for its pathogenicity in humans, being implicated in a variety of serious health effects, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The extensive list of infections associated with SIKP008 underscores its clinical significance and the public health challenges it poses. As a free-living organism with the capability for opportunistic infections, K. pneumoniae strain SIKP008 exemplifies the complex interactions between environmental microbes and host organisms. Its versatile metabolism and ability to adapt to various hosts may facilitate its persistence in diverse ecological settings, raising concerns regarding its management in clinical environments and its impact on health across species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP008 9_NODE_96

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP008 9_NODE_96
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP008 9_NODE_96, whole genome

Gene Summary

Adenine Count

1195691 bp

Thymine Count

1197370 bp

Guanine Count

1582599 bp

Cytosine Count

1613248 bp

Genome Length

5588908 bp

Protein-coding Genes

5115 genes

Non-Coding Genes

402 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf4752 family proteinFAM68_28345Not AvailableNegative5584042 - 55841313169.76
is6-like element is26 family transposaseFAM68_28350Not AvailableNegative5584184 - 558488827896.9
transketolaseFAM68_28355Not AvailableNegative5584953 - 558574028639.9
Trna-alaNot AvailableNot AvailablePositive5586131 - 5586206Not Available
Trna-ileNot AvailableNot AvailablePositive5586243 - 5586319Not Available
hypothetical proteinFAM68_28380Not AvailableNegative5586445 - 558709622868.6
elongation factor tuFAM68_28385Not AvailablePositive5587749 - 558838623547.5

Displaying genes 5511 – 5517 of 5517 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total