Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100 is a Gram-negative, rod-shaped bacterium characterized as a chemoheterotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It typically resides in host-associated environments and is known to be a free-living organism. In terms of cell arrangement, SIKP004 can be found in chains, pairs, or as single cells. It possesses flagella, indicating motility, which may play a role in its ability to colonize hosts and environments. The bacterium is mesophilic, with an optimal growth temperature of 37°C, aligning with the typical body temperature of warm-blooded hosts. Klebsiella pneumoniae subsp. pneumoniae is clinically significant, as it is associated with pneumonia and community-acquired pneumonia (CAP), highlighting its potential impact on human health. The strain has a single circular replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Overall, the ecological role of SIKP004 extends beyond mere survival, as its pathogenic potential in causing pneumonia underlines the importance of understanding its biology and behavior in host-associated environments. This insight is crucial for developing strategies for prevention and treatment of infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP004 4_NODE_100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100,

Gene Summary

Adenine Count

1241297 bp

Thymine Count

1227890 bp

Guanine Count

1616098 bp

Cytosine Count

1652623 bp

Genome Length

5737908 bp

Protein-coding Genes

5197 genes

Non-Coding Genes

407 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-cystine transporterFAM77_23205Not AvailableNegative4669503 - 467089448821.8
metal-dependent hydrolaseFAM77_23210Not AvailableNegative4671030 - 467162021850.9
2-dehydro-3-deoxy-d-gluconate 5-dehydrogenase kdudFAM77_23215Not AvailableNegative4671712 - 467247326908.3
hexitol phosphatase hxpbFAM77_23220Not AvailableNegative4672623 - 467329124487.8
hypothetical proteinFAM77_23225Not AvailablePositive4673480 - 467401620533.8
acyl-coa thioester hydrolase yciaFAM77_23230Not AvailableNegative4674046 - 467444414291.5
tonb-dependent siderophore receptorFAM77_23235Not AvailableNegative4674544 - 467672780089.2
sodium ion-translocating decarboxylase subunit betaFAM77_23245Not AvailablePositive4677099 - 46772545156.54
sensor histidine kinaseFAM77_23250Not AvailablePositive4677426 - 467905461203.0
response regulatorFAM77_23255Not AvailablePositive4679047 - 467975126822.1

Displaying genes 4691 – 4700 of 5604 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total