Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100 is a Gram-negative, rod-shaped bacterium characterized as a chemoheterotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It typically resides in host-associated environments and is known to be a free-living organism. In terms of cell arrangement, SIKP004 can be found in chains, pairs, or as single cells. It possesses flagella, indicating motility, which may play a role in its ability to colonize hosts and environments. The bacterium is mesophilic, with an optimal growth temperature of 37°C, aligning with the typical body temperature of warm-blooded hosts. Klebsiella pneumoniae subsp. pneumoniae is clinically significant, as it is associated with pneumonia and community-acquired pneumonia (CAP), highlighting its potential impact on human health. The strain has a single circular replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Overall, the ecological role of SIKP004 extends beyond mere survival, as its pathogenic potential in causing pneumonia underlines the importance of understanding its biology and behavior in host-associated environments. This insight is crucial for developing strategies for prevention and treatment of infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP004 4_NODE_100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100,

Gene Summary

Adenine Count

1241297 bp

Thymine Count

1227890 bp

Guanine Count

1616098 bp

Cytosine Count

1652623 bp

Genome Length

5737908 bp

Protein-coding Genes

5197 genes

Non-Coding Genes

407 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cytosol nonspecific dipeptidaseFAM77_22430Not AvailablePositive4517767 - 451922452450.8
gnat family n-acetyltransferaseFAM77_22435Not AvailableNegative4519267 - 451971916774.3
dna polymerase ivFAM77_22440Not AvailableNegative4519722 - 452077739581.1
glycerophosphodiester phosphodiesteraseFAM77_22445Not AvailablePositive4520937 - 452179731608.5
(na+)-nqr maturation nqrmFAM77_22450Not AvailableNegative4522020 - 45222357902.99
nadh:ubiquinone reductase (na(+)-transporting) subunit fFAM77_22455Not AvailableNegative4522238 - 452346145284.5
nadh:ubiquinone reductase (na(+)-transporting) subunit eFAM77_22460Not AvailableNegative4523474 - 452407021291.9
nadh:ubiquinone reductase (na(+)-transporting) subunit dFAM77_22465Not AvailableNegative4524077 - 452471523030.9
na(+)-translocating nadh-quinone reductase subunit cFAM77_22470Not AvailableNegative4524708 - 452550228398.2
nadh:ubiquinone reductase (na(+)-transporting) subunit bFAM77_22475Not AvailableNegative4525495 - 452673345048.7

Displaying genes 4541 – 4550 of 5604 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total