Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100 is a Gram-negative, rod-shaped bacterium characterized as a chemoheterotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It typically resides in host-associated environments and is known to be a free-living organism. In terms of cell arrangement, SIKP004 can be found in chains, pairs, or as single cells. It possesses flagella, indicating motility, which may play a role in its ability to colonize hosts and environments. The bacterium is mesophilic, with an optimal growth temperature of 37°C, aligning with the typical body temperature of warm-blooded hosts. Klebsiella pneumoniae subsp. pneumoniae is clinically significant, as it is associated with pneumonia and community-acquired pneumonia (CAP), highlighting its potential impact on human health. The strain has a single circular replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Overall, the ecological role of SIKP004 extends beyond mere survival, as its pathogenic potential in causing pneumonia underlines the importance of understanding its biology and behavior in host-associated environments. This insight is crucial for developing strategies for prevention and treatment of infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP004 4_NODE_100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100,

Gene Summary

Adenine Count

1241297 bp

Thymine Count

1227890 bp

Guanine Count

1616098 bp

Cytosine Count

1652623 bp

Genome Length

5737908 bp

Protein-coding Genes

5197 genes

Non-Coding Genes

407 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
23s rrna pseudouridine(2604) synthase rlufFAM77_16565Not AvailableNegative3359067 - 335994232558.5
sugar-binding transcriptional regulatorFAM77_16570Not AvailablePositive3360292 - 336123935020.9
sdr family oxidoreductaseFAM77_16575Not AvailablePositive3361310 - 336211329046.6
pts sugar transporter subunit iiaFAM77_16580Not AvailablePositive3362123 - 336253014508.3
sorbose-specific phosphotransferase enzyme iib componentFAM77_16585Not AvailablePositive3362530 - 336302418457.4
pts mannose/fructose/sorbose transporter subunit iicFAM77_16590Not AvailablePositive3363090 - 336389027776.7
pts system mannose/fructose/sorbose family transporter subunit iidFAM77_16595Not AvailablePositive3363902 - 336472629183.6
l-sorbose 1-phosphate reductaseFAM77_16600Not AvailablePositive3364799 - 336603144799.4
shikimate 5-dehydrogenaseFAM77_16605Not AvailablePositive3366024 - 336683328727.8
na/pi cotransporter family proteinFAM77_16610Not AvailableNegative3366921 - 336855259433.5

Displaying genes 3581 – 3590 of 5604 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total