Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100 is a Gram-negative, rod-shaped bacterium characterized as a chemoheterotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It typically resides in host-associated environments and is known to be a free-living organism. In terms of cell arrangement, SIKP004 can be found in chains, pairs, or as single cells. It possesses flagella, indicating motility, which may play a role in its ability to colonize hosts and environments. The bacterium is mesophilic, with an optimal growth temperature of 37°C, aligning with the typical body temperature of warm-blooded hosts. Klebsiella pneumoniae subsp. pneumoniae is clinically significant, as it is associated with pneumonia and community-acquired pneumonia (CAP), highlighting its potential impact on human health. The strain has a single circular replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Overall, the ecological role of SIKP004 extends beyond mere survival, as its pathogenic potential in causing pneumonia underlines the importance of understanding its biology and behavior in host-associated environments. This insight is crucial for developing strategies for prevention and treatment of infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP004 4_NODE_100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100,

Gene Summary

Adenine Count

1241297 bp

Thymine Count

1227890 bp

Guanine Count

1616098 bp

Cytosine Count

1652623 bp

Genome Length

5737908 bp

Protein-coding Genes

5197 genes

Non-Coding Genes

407 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
5-methyltetrahydropteroyltriglutamate-- homocysteine s-methyltransferaseFAM77_09175Not AvailablePositive1894612 - 189571541271.5
urea abc transporter substrate-binding proteinFAM77_09180Not AvailablePositive1895887 - 189715846227.2
urea abc transporter permease subunit urtbFAM77_09185Not AvailablePositive1897220 - 189879455856.6
urea abc transporter permease subunit urtcFAM77_09190Not AvailablePositive1898794 - 189986738717.7
urea abc transporter atp-binding protein urtdFAM77_09195Not AvailablePositive1899867 - 190066429298.2
urea abc transporter atp-binding subunit urteFAM77_09200Not AvailablePositive1900674 - 190137225704.3
helix-turn-helix domain-containing proteinFAM77_09205Not AvailableNegative1901408 - 190189018332.2
efflux mfs transporter ydeeFAM77_09210Not AvailableNegative1902020 - 190321643258.0
multiple antibiotic resistance protein marbFAM77_09220Not AvailableNegative1904360 - 19045788030.34
mdr efflux pump acrab transcriptional activator maraFAM77_09225Not AvailableNegative1904619 - 190499314698.5

Displaying genes 2131 – 2140 of 5604 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total