Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100 is a Gram-negative, rod-shaped bacterium characterized as a chemoheterotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It typically resides in host-associated environments and is known to be a free-living organism. In terms of cell arrangement, SIKP004 can be found in chains, pairs, or as single cells. It possesses flagella, indicating motility, which may play a role in its ability to colonize hosts and environments. The bacterium is mesophilic, with an optimal growth temperature of 37°C, aligning with the typical body temperature of warm-blooded hosts. Klebsiella pneumoniae subsp. pneumoniae is clinically significant, as it is associated with pneumonia and community-acquired pneumonia (CAP), highlighting its potential impact on human health. The strain has a single circular replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Overall, the ecological role of SIKP004 extends beyond mere survival, as its pathogenic potential in causing pneumonia underlines the importance of understanding its biology and behavior in host-associated environments. This insight is crucial for developing strategies for prevention and treatment of infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP004 4_NODE_100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP004 4_NODE_100,

Gene Summary

Adenine Count

1241297 bp

Thymine Count

1227890 bp

Guanine Count

1616098 bp

Cytosine Count

1652623 bp

Genome Length

5737908 bp

Protein-coding Genes

5197 genes

Non-Coding Genes

407 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
isochorismate synthase menfFAM77_06475Not AvailablePositive1331385 - 133267447579.8
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthaseFAM77_06480Not AvailablePositive1332757 - 133442760593.4
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthaseFAM77_06485Not AvailablePositive1334424 - 133518227725.8
1,4-dihydroxy-2-naphthoyl-coa synthaseFAM77_06490Not AvailablePositive1335197 - 133605431626.8
o-succinylbenzoate synthaseFAM77_06495Not AvailablePositive1336054 - 133701935171.5
o-succinylbenzoate--coa ligaseFAM77_06500Not AvailablePositive1337016 - 133839249783.1
nucleoside triphosphatase nudiFAM77_06505Not AvailableNegative1338448 - 133887316231.4
rpn family recombination-promoting nuclease/putative transposaseFAM77_06510Not AvailablePositive1339011 - 133996436207.9
hypothetical proteinFAM77_06515Not AvailablePositive1340239 - 134078118647.8
nicotinamide mononucleotide deamidase-related protein yfayFAM77_06520Not AvailablePositive1340884 - 134208043389.5

Displaying genes 1601 – 1610 of 5604 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total