Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 (accession SSYK00000000.1) is a Gram-negative, rod-shaped bacterium that primarily exists in host-associated environments. As a facultative anaerobe, it can thrive in both the presence and absence of oxygen, making it adaptable to various ecological niches. The organism is classified as a chemoheterotroph, deriving its energy from organic compounds. This strain exhibits a unique cell arrangement, commonly found in chains, pairs, and singles, which may facilitate its survival and proliferation in host environments. The bacterium possesses flagella, indicating mobility, which can enhance its ability to colonize hosts and evade immune responses. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, aligning with the human body temperature, which is significant given its association with community-acquired pneumonia (CAP). Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 is nonsporulating and has two membranes, characteristic of Gram-negative bacteria, which may provide advantages in terms of resistance to certain antibiotics and environmental stresses. The bacterium is known to have a free-living biotic relationship, indicating its ability to exist independently in various environments. The ecological insight from SIKP044 is its potential role in human health, particularly in respiratory infections. Its adaptability and mobility suggest that it can easily move between different ecological niches, including those associated with human hosts, thereby contributing to its status as a significant pathogen in community-acquired pneumonia. Understanding its traits can inform strategies for managing infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP044 49_NODE_80

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80,

Gene Summary

Adenine Count

1189891 bp

Thymine Count

1193484 bp

Guanine Count

1581537 bp

Cytosine Count

1590974 bp

Genome Length

5555886 bp

Protein-coding Genes

5083 genes

Non-Coding Genes

405 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Major tail shaft subunitFAM70_24795Not AvailableNegative4983068 - 498352916026.3
Gp11FAM70_24800Not AvailableNegative4983561 - 498396214904.2
Gp10FAM70_24805Not AvailableNegative4983959 - 498434814803.9
Gp9FAM70_24810Not AvailableNegative4984329 - 498466712571.1
Head-tail connector proteinFAM70_24815Not AvailableNegative4984664 - 498498112105.5
Gp7FAM70_24820Not AvailableNegative4984962 - 49852349996.63
Major capsid head protein precursorFAM70_24825Not AvailableNegative4985293 - 498657945944.9
Putative head maturation proteaseFAM70_24830Not AvailableNegative4986657 - 498757732861.4
Putative portal proteinFAM70_24835Not AvailableNegative4987614 - 498887347335.1
Gp3FAM70_24840Not AvailableNegative4988873 - 49890525847.28

Displaying genes 361 – 370 of 5488 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total