Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 (accession SSYK00000000.1) is a Gram-negative, rod-shaped bacterium that primarily exists in host-associated environments. As a facultative anaerobe, it can thrive in both the presence and absence of oxygen, making it adaptable to various ecological niches. The organism is classified as a chemoheterotroph, deriving its energy from organic compounds. This strain exhibits a unique cell arrangement, commonly found in chains, pairs, and singles, which may facilitate its survival and proliferation in host environments. The bacterium possesses flagella, indicating mobility, which can enhance its ability to colonize hosts and evade immune responses. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, aligning with the human body temperature, which is significant given its association with community-acquired pneumonia (CAP). Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 is nonsporulating and has two membranes, characteristic of Gram-negative bacteria, which may provide advantages in terms of resistance to certain antibiotics and environmental stresses. The bacterium is known to have a free-living biotic relationship, indicating its ability to exist independently in various environments. The ecological insight from SIKP044 is its potential role in human health, particularly in respiratory infections. Its adaptability and mobility suggest that it can easily move between different ecological niches, including those associated with human hosts, thereby contributing to its status as a significant pathogen in community-acquired pneumonia. Understanding its traits can inform strategies for managing infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP044 49_NODE_80

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80,

Gene Summary

Adenine Count

1189891 bp

Thymine Count

1193484 bp

Guanine Count

1581537 bp

Cytosine Count

1590974 bp

Genome Length

5555886 bp

Protein-coding Genes

5083 genes

Non-Coding Genes

405 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dipeptide abc transporter atp binding subunit dppfFAM70_11435Not AvailablePositive2279088 - 228010137660.9
hypothetical proteinFAM70_11440Not AvailablePositive2280120 - 22802997060.88
cellulose biosynthesis protein bcsoFAM70_11445Not AvailablePositive2280617 - 228115618799.1
cellulose synthase operon protein yhjqFAM70_11450Not AvailablePositive2281147 - 228195028839.7
udp-forming cellulose synthase catalytic subunitFAM70_11455Not AvailablePositive2281970 - 228408179490.5
cellulose biosynthesis cyclic di-gmp-binding regulatory protein bcsbFAM70_11460Not AvailablePositive2284078 - 228650487493.1
tetratricopeptide repeat proteinFAM70_11465Not AvailablePositive2286501 - 2290553145052.0
cellulose synthaseFAM70_11470Not AvailablePositive2290553 - 229102917937.4
endoglucanaseFAM70_11475Not AvailablePositive2291041 - 229204237654.1
cellulose biosynthesis protein bcsgFAM70_11480Not AvailableNegative2292150 - 229382961908.2

Displaying genes 2421 – 2430 of 5488 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total