Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 (accession SSYK00000000.1) is a Gram-negative, rod-shaped bacterium that primarily exists in host-associated environments. As a facultative anaerobe, it can thrive in both the presence and absence of oxygen, making it adaptable to various ecological niches. The organism is classified as a chemoheterotroph, deriving its energy from organic compounds. This strain exhibits a unique cell arrangement, commonly found in chains, pairs, and singles, which may facilitate its survival and proliferation in host environments. The bacterium possesses flagella, indicating mobility, which can enhance its ability to colonize hosts and evade immune responses. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, aligning with the human body temperature, which is significant given its association with community-acquired pneumonia (CAP). Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 is nonsporulating and has two membranes, characteristic of Gram-negative bacteria, which may provide advantages in terms of resistance to certain antibiotics and environmental stresses. The bacterium is known to have a free-living biotic relationship, indicating its ability to exist independently in various environments. The ecological insight from SIKP044 is its potential role in human health, particularly in respiratory infections. Its adaptability and mobility suggest that it can easily move between different ecological niches, including those associated with human hosts, thereby contributing to its status as a significant pathogen in community-acquired pneumonia. Understanding its traits can inform strategies for managing infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP044 49_NODE_80

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP044 49_NODE_80,

Gene Summary

Adenine Count

1189891 bp

Thymine Count

1193484 bp

Guanine Count

1581537 bp

Cytosine Count

1590974 bp

Genome Length

5555886 bp

Protein-coding Genes

5083 genes

Non-Coding Genes

405 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transposaseFAM70_08145Not AvailablePositive1638924 - 163941519923.7
lysophospholipid acyltransferase family proteinFAM70_08150Not AvailablePositive1639596 - 164131465218.5
taurine dioxygenaseFAM70_08155Not AvailableNegative1641482 - 164233332367.1
taurine abc transporter permease taucFAM70_08160Not AvailableNegative1642330 - 164315729427.3
taurine abc transporter atp-binding subunitFAM70_08165Not AvailableNegative1643154 - 164392128127.2
taurine abc transporter substrate-binding proteinFAM70_08170Not AvailableNegative1643933 - 164489534188.8
homocysteine s-methyltransferaseFAM70_08175Not AvailableNegative1645135 - 164606733156.3
s-methylmethionine permeaseFAM70_08180Not AvailableNegative1646054 - 164746350795.0
ethanolamine permeaseFAM70_08185Not AvailablePositive1647737 - 164911649004.1
ethanolamine ammonia-lyase subunit eutbFAM70_08190Not AvailablePositive1649126 - 165051449928.2

Displaying genes 1901 – 1910 of 5488 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total