Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79 is a Gram-negative bacterium that exhibits a rod shape and typically arranges itself in chains, pairs, or singles. This strain is classified as a chemoheterotroph, relying on organic compounds for energy, and it demonstrates facultative anaerobic characteristics, allowing it to thrive in both aerobic and anaerobic conditions. With mobility facilitated by the presence of flagella, SIKP040 can navigate its environment effectively. The optimal growth temperature for this mesophilic organism is 37°C, which aligns with the temperature of the human body, suggesting an adaptation to a host-associated habitat. This ecological niche is significant as K. pneumoniae is known to be a pathogen associated with pneumonia, particularly community-acquired pneumonia (CAP). SIKP040 has a single replicon and possesses two membranes, typical of Gram-negative bacteria. Importantly, this strain does not undergo sporulation, indicating that it reproduces through binary fission instead. As a free-living bacterium, it can exist independently in the environment, yet its pathogenic potential highlights the dual role of this organism as both a member of the microbiota and a potential threat to human health. In summary, Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79 exemplifies a versatile organism with significant implications for human health, particularly in the context of respiratory infections. Its adaptability to various environments and its pathogenic capabilities underscore the importance of monitoring and understanding this strain in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP040 44_NODE_79

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79,

Gene Summary

Adenine Count

1178497 bp

Thymine Count

1182712 bp

Guanine Count

1594514 bp

Cytosine Count

1566434 bp

Genome Length

5522157 bp

Protein-coding Genes

5103 genes

Non-Coding Genes

351 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
der gtpase-activating protein yihiFAM32_21195Not AvailableNegative4308566 - 430907218780.9
yiha family ribosome biogenesis gtp-binding proteinFAM32_21200Not AvailablePositive4309656 - 431028823533.3
dna polymerase iFAM32_21205Not AvailableNegative4310636 - 4313428103187.0
acyltransferaseFAM32_21210Not AvailablePositive4313825 - 431472434968.2
thiol:disulfide interchange protein dsbaFAM32_21215Not AvailableNegative4314773 - 431539622946.6
serine/threonine protein kinaseFAM32_21220Not AvailableNegative4315424 - 431641038414.6
duf1040 family proteinFAM32_21225Not AvailableNegative4316486 - 431675510323.5
molybdenum cofactor guanylyltransferase mobaFAM32_21230Not AvailablePositive4316827 - 431740821556.0
molybdopterin-guanine dinucleotide biosynthesis protein bFAM32_21235Not AvailablePositive4317405 - 431791118717.8
menaquinone-dependent protoporphyrinogen ix dehydrogenaseFAM32_21240Not AvailableNegative4318429 - 431896220573.8

Displaying genes 4281 – 4290 of 5454 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total