Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79 is a Gram-negative bacterium that exhibits a rod shape and typically arranges itself in chains, pairs, or singles. This strain is classified as a chemoheterotroph, relying on organic compounds for energy, and it demonstrates facultative anaerobic characteristics, allowing it to thrive in both aerobic and anaerobic conditions. With mobility facilitated by the presence of flagella, SIKP040 can navigate its environment effectively. The optimal growth temperature for this mesophilic organism is 37°C, which aligns with the temperature of the human body, suggesting an adaptation to a host-associated habitat. This ecological niche is significant as K. pneumoniae is known to be a pathogen associated with pneumonia, particularly community-acquired pneumonia (CAP). SIKP040 has a single replicon and possesses two membranes, typical of Gram-negative bacteria. Importantly, this strain does not undergo sporulation, indicating that it reproduces through binary fission instead. As a free-living bacterium, it can exist independently in the environment, yet its pathogenic potential highlights the dual role of this organism as both a member of the microbiota and a potential threat to human health. In summary, Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79 exemplifies a versatile organism with significant implications for human health, particularly in the context of respiratory infections. Its adaptability to various environments and its pathogenic capabilities underscore the importance of monitoring and understanding this strain in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP040 44_NODE_79

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP040 44_NODE_79,

Gene Summary

Adenine Count

1178497 bp

Thymine Count

1182712 bp

Guanine Count

1594514 bp

Cytosine Count

1566434 bp

Genome Length

5522157 bp

Protein-coding Genes

5103 genes

Non-Coding Genes

351 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aquaporinFAM32_11385Not AvailableNegative2313648 - 231445128030.8
diol dehydratase reactivase subunit alphaFAM32_11390Not AvailableNegative2314505 - 231632863608.3
glycerol dehydratase small subunit dhab3FAM32_11395Not AvailableNegative2316341 - 231676616105.3
propanediol/glycerol family dehydratase medium subunitFAM32_11400Not AvailableNegative2316769 - 231735321342.7
propanediol/glycerol family dehydratase large subunitFAM32_11405Not AvailableNegative2317366 - 231903360721.4
heme-binding proteinFAM32_11410Not AvailablePositive2319447 - 231987515010.1
iron-containing alcohol dehydrogenaseFAM32_11415Not AvailablePositive2319897 - 232106041453.0
hypothetical proteinFAM32_11420Not AvailablePositive2321081 - 232143412004.2
cob(i)yrinic acid a,c-diamide adenosyltransferaseFAM32_11425Not AvailablePositive2321435 - 232196519716.6
pts-dependent dihydroxyacetone kinase operon transcriptional regulator dharFAM32_11430Not AvailableNegative2321943 - 232386870947.0

Displaying genes 2431 – 2440 of 5454 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total