Klebsiella pneumoniae strain SIKP039 43_NODE_86

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP039 43_NODE_86 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in various arrangements, including chains, pairs, and singles. SIKP039 is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for survival in warm-blooded hosts. This strain is associated with a range of hosts, including Homo sapiens, Gallus gallus, and several other species across Metazoa and Viridiplantae, indicating its ecological versatility. SIKP039 is known to cause a variety of health issues in humans, including bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The bacterium is nonsporulating and possesses a single replicon with two membranes, a typical feature of Gram-negative bacteria. Given its pathogenicity primarily towards humans and its ability to inhabit diverse environments, Klebsiella pneumoniae strain SIKP039 underscores the importance of monitoring its presence in clinical settings and the potential risks it poses in both human health and veterinary contexts. This adaptability and range of pathogenic effects highlight the need for comprehensive strategies in infection control and antibiotic management to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP039 43_NODE_86

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP039 43_NODE_86
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP039 43_NODE_86, whole genome

Gene Summary

Adenine Count

1174374 bp

Thymine Count

1187479 bp

Guanine Count

1604620 bp

Cytosine Count

1557203 bp

Genome Length

5523676 bp

Protein-coding Genes

5106 genes

Non-Coding Genes

343 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
shikimate dehydrogenaseFAM28_25795Not AvailablePositive5189228 - 519004629087.9
duf1488 domain-containing proteinFAM28_25800Not AvailablePositive5190043 - 51903009675.19
gamma carbonic anhydrase family proteinFAM28_25805Not AvailableNegative5190276 - 519083020181.3
Trna-asnNot AvailableNot AvailablePositive5191211 - 5191285Not Available
Trna-pheNot AvailableNot AvailablePositive5191292 - 5191367Not Available
Trna-thrNot AvailableNot AvailablePositive5191373 - 5191448Not Available
Trna-argNot AvailableNot AvailablePositive5191454 - 5191530Not Available
hypothetical proteinFAM28_25990Not AvailablePositive5216404 - 521717626759.8
ctx-m family class a extended-spectrum beta-lactamaseFAM28_25995Not AvailablePositive5217177 - 521796527981.3
cupin fold metalloprotein, wbuc familyFAM28_26000Not AvailableNegative5218012 - 521834412100.3

Displaying genes 5131 – 5140 of 5449 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total