Klebsiella pneumoniae strain SIKP038 42_NODE_96

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP038 (accession SSYE00000000.1) is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and is categorized as a chemoheterotroph. This strain is notable for its ability to grow in various environments associated with multiple hosts, including Homo sapiens, Gallus gallus, and other Metazoa and Viridiplantae. It typically exists in chains, pairs, or as single cells, and it possesses flagella, which contributes to its mobility. SIKP038 thrives optimally at 37°C, fitting within the mesophilic temperature range. This strain has a single replicon and is characterized by a double membrane structure. As a free-living organism, it can inhabit diverse ecological niches while being capable of causing a range of serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The pathogenicity of Klebsiella pneumoniae is particularly concerning due to its association with severe infections, such as sepsis and pneumonia, which can lead to significant morbidity and mortality. The strain's capacity to infect multiple hosts, including domesticated animals and humans, highlights its ecological versatility and potential for zoonotic transmission. Understanding the traits of SIKP038 is crucial for addressing its clinical implications and exploring strategies for infection control and management in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP038 42_NODE_96

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP038 42_NODE_96
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP038 42_NODE_96, whole genome

Gene Summary

Adenine Count

1181046 bp

Thymine Count

1176847 bp

Guanine Count

1552776 bp

Cytosine Count

1604271 bp

Genome Length

5514940 bp

Protein-coding Genes

5157 genes

Non-Coding Genes

281 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinFAM29_19710Not AvailableNegative4067014 - 40672689440.26
Putative head-tail joining proteinFAM29_19715Not AvailableNegative4067270 - 406766514328.0
hypothetical proteinFAM29_19720Not AvailableNegative4067706 - 40679788625.77
Major capsid proteinFAM29_19725Not AvailableNegative4067987 - 406894034216.2
Hypothetical proteinFAM29_19730Not AvailableNegative4068951 - 406973027818.8
Head morphogenesis proteinFAM29_19735Not AvailableNegative4070243 - 407135541168.7
Putative portal vertex proteinFAM29_19740Not AvailableNegative4071339 - 407273951706.6
Hypothetical proteinFAM29_19745Not AvailableNegative4072741 - 407405449774.9
Terminase small subunitFAM29_19750Not AvailableNegative4074038 - 407503337421.0
Hypothetical proteinFAM29_19755Not AvailableNegative4075977 - 40761717038.52

Displaying genes 11 – 20 of 5438 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total