Klebsiella pneumoniae subsp. pneumoniae strain 64

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 64 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain typically inhabits host-associated environments and exhibits a diverse cell arrangement, appearing in chains, pairs, and singles. It possesses flagella, which contributes to its mobility, allowing it to navigate through various environments effectively. The optimal growth temperature for this strain is 37°C, positioning it within the mesophilic temperature range, which is conducive to the survival and replication of many pathogenic microorganisms. Notably, Klebsiella pneumoniae subsp. pneumoniae strain 64 is nonsporulating, meaning it does not form spores as a survival mechanism, which is characteristic of some other bacteria. This strain is associated with significant health effects, particularly in causing pneumonia and community-acquired pneumonia (CAP), making it a notable pathogen in clinical settings. Its ability to thrive in host-associated environments while being free-living highlights its ecological versatility. With a single replicon and a double membrane structure, the strain's cellular organization is consistent with that of many other members of the Enterobacteriaceae family. The pathogenicity of Klebsiella pneumoniae subsp. pneumoniae strain 64, combined with its environmental adaptability, underscores the importance of monitoring and understanding its behavior in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 64

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 64
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 64

Gene Summary

Adenine Count

1273400 bp

Thymine Count

1274437 bp

Guanine Count

1669165 bp

Cytosine Count

1661695 bp

Genome Length

5878697 bp

Protein-coding Genes

5446 genes

Non-Coding Genes

309 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
branched-chain amino acid abc transporter substrate-binding proteinE9159_16070Not AvailablePositive3291316 - 329241938878.5
aspartate 1-decarboxylase autocleavage activator panmE9159_16075Not AvailableNegative3292939 - 329332214562.3
hypothetical proteinE9159_16080Not AvailableNegative3293571 - 32937145554.04
high-affinity branched-chain amino acid abc transporter substrate-binding protein livkE9159_16085Not AvailablePositive3293746 - 329485539443.2
high-affinity branched-chain amino acid abc transporter permease livhE9159_16090Not AvailablePositive3294917 - 329584333014.5
high-affinity branched-chain amino acid abc transporter permease livmE9159_16095Not AvailablePositive3295840 - 329711746411.4
high-affinity branched-chain amino acid abc transporter atp-binding protein livgE9159_16100Not AvailablePositive3297114 - 329788128412.7
high-affinity branched-chain amino acid abc transporter atp-binding protein livfE9159_16105Not AvailablePositive3297883 - 329859626210.8
type ii toxin-antitoxin system phd/yefm family antitoxinE9159_16110Not AvailablePositive3298760 - 32989818151.61
type ii toxin-antitoxin system death-on-curing family toxinE9159_16115Not AvailablePositive3298978 - 329934613553.8

Displaying genes 3321 – 3330 of 5755 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total