Klebsiella pneumoniae subsp. pneumoniae strain 64

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 64 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain typically inhabits host-associated environments and exhibits a diverse cell arrangement, appearing in chains, pairs, and singles. It possesses flagella, which contributes to its mobility, allowing it to navigate through various environments effectively. The optimal growth temperature for this strain is 37°C, positioning it within the mesophilic temperature range, which is conducive to the survival and replication of many pathogenic microorganisms. Notably, Klebsiella pneumoniae subsp. pneumoniae strain 64 is nonsporulating, meaning it does not form spores as a survival mechanism, which is characteristic of some other bacteria. This strain is associated with significant health effects, particularly in causing pneumonia and community-acquired pneumonia (CAP), making it a notable pathogen in clinical settings. Its ability to thrive in host-associated environments while being free-living highlights its ecological versatility. With a single replicon and a double membrane structure, the strain's cellular organization is consistent with that of many other members of the Enterobacteriaceae family. The pathogenicity of Klebsiella pneumoniae subsp. pneumoniae strain 64, combined with its environmental adaptability, underscores the importance of monitoring and understanding its behavior in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 64

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 64
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 64

Gene Summary

Adenine Count

1273400 bp

Thymine Count

1274437 bp

Guanine Count

1669165 bp

Cytosine Count

1661695 bp

Genome Length

5878697 bp

Protein-coding Genes

5446 genes

Non-Coding Genes

309 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nickel abc transporter permease subunit nikcE9159_15920Not AvailableNegative3260896 - 326172930184.9
nickel abc transporter permease subunit nikbE9159_15925Not AvailableNegative3261726 - 326267035303.4
nickel abc transporter, nickel/metallophore periplasmic binding proteinE9159_15930Not AvailableNegative3262670 - 326423858205.6
hypothetical proteinE9159_15935Not AvailablePositive3264265 - 32644446303.63
lysr family transcriptional regulatorE9159_15940Not AvailableNegative3264377 - 326523732002.5
phenolic acid decarboxylaseE9159_15945Not AvailablePositive3265338 - 326584119072.4
udp-4-amino-4-deoxy-l-arabinose aminotransferaseE9159_15950Not AvailablePositive3266238 - 326737741278.4
undecaprenyl-phosphate 4-deoxy-4-formamido-l-arabinose transferaseE9159_15955Not AvailablePositive3267379 - 326836236695.8
bifunctional udp-4-amino-4-deoxy-l-arabinose formyltransferase/udp-glucuronic acid oxidase arnaE9159_15960Not AvailablePositive3268359 - 327034474064.7
4-deoxy-4-formamido-l-arabinose- phosphoundecaprenol deformylaseE9159_15965Not AvailablePositive3270341 - 327124333381.0

Displaying genes 3291 – 3300 of 5755 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total