Klebsiella pneumoniae subsp. pneumoniae strain 64

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 64 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain typically inhabits host-associated environments and exhibits a diverse cell arrangement, appearing in chains, pairs, and singles. It possesses flagella, which contributes to its mobility, allowing it to navigate through various environments effectively. The optimal growth temperature for this strain is 37°C, positioning it within the mesophilic temperature range, which is conducive to the survival and replication of many pathogenic microorganisms. Notably, Klebsiella pneumoniae subsp. pneumoniae strain 64 is nonsporulating, meaning it does not form spores as a survival mechanism, which is characteristic of some other bacteria. This strain is associated with significant health effects, particularly in causing pneumonia and community-acquired pneumonia (CAP), making it a notable pathogen in clinical settings. Its ability to thrive in host-associated environments while being free-living highlights its ecological versatility. With a single replicon and a double membrane structure, the strain's cellular organization is consistent with that of many other members of the Enterobacteriaceae family. The pathogenicity of Klebsiella pneumoniae subsp. pneumoniae strain 64, combined with its environmental adaptability, underscores the importance of monitoring and understanding its behavior in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 64

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 64
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 64

Gene Summary

Adenine Count

1273400 bp

Thymine Count

1274437 bp

Guanine Count

1669165 bp

Cytosine Count

1661695 bp

Genome Length

5878697 bp

Protein-coding Genes

5446 genes

Non-Coding Genes

309 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
iron abc transporter permeaseE9159_14830Not AvailableNegative3039391 - 304039835119.2
hypothetical proteinE9159_14835Not AvailableNegative3040388 - 304144639343.5
dna-binding transcriptional activator mhprE9159_14840Not AvailableNegative3041538 - 304235030674.9
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylaseE9159_14845Not AvailablePositive3042528 - 304419261458.3
3-carboxyethylcatechol 2,3-dioxygenaseE9159_14850Not AvailablePositive3044194 - 304513834419.2
alpha/beta fold hydrolaseE9159_14855Not AvailablePositive3045156 - 304602231741.1
2-keto-4-pentenoate hydrataseE9159_14860Not AvailablePositive3046033 - 304683928679.3
acetaldehyde dehydrogenase (acetylating)E9159_14865Not AvailablePositive3046832 - 304778232946.9
4-hydroxy-2-oxovalerate aldolaseE9159_14870Not AvailablePositive3047779 - 304879535983.3
3-(3-hydroxy-phenyl)propionate transporter mhptE9159_14875Not AvailablePositive3048871 - 305006741009.2

Displaying genes 3081 – 3090 of 5755 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total