Klebsiella pneumoniae subsp. pneumoniae strain 63

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 63 is a significant pathogen known for its role in community-acquired pneumonia (CAP). This Gram-negative bacterium exhibits a rod-shaped morphology and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, it derives energy from organic compounds, making it well-suited for its host-associated habitat. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, fitting within the mesophilic temperature range. The bacterium is motile, possessing flagella, which may contribute to its ability to colonize various niches within host organisms. Klebsiella pneumoniae subsp. pneumoniae strain 63 has a simple genomic structure, featuring one replicon and two membranes. It does not form spores, indicating a reliance on its immediate environment for survival and reproduction. In terms of biotic relationships, it is classified as free-living, suggesting that while it can inhabit hosts, it may also exist independently in other environments. Understanding the ecological role of this strain is crucial, as it is associated with significant health effects such as pneumonia. Its adaptability to varying oxygen levels and temperature, along with its motility, likely enhances its pathogenic potential in human hosts. The presence of strain 63 in clinical settings underscores the importance of monitoring this bacterium to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 63

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 63
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 63

Gene Summary

Adenine Count

1250203 bp

Thymine Count

1248591 bp

Guanine Count

1631171 bp

Cytosine Count

1641410 bp

Genome Length

5771375 bp

Protein-coding Genes

5304 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf2756 family proteinE9164_21115Not AvailablePositive4281355 - 428167511967.3
glycerophosphodiester phosphodiesteraseE9164_21120Not AvailableNegative4281699 - 428243927127.6
sn-glycerol-3-phosphate import atp-binding protein ugpcE9164_21125Not AvailableNegative4282436 - 428350639722.7
sn-glycerol-3-phosphate abc transporter permease ugpeE9164_21130Not AvailableNegative4283508 - 428435331411.7
sn-glycerol-3-phosphate abc transporter permease ugpaE9164_21135Not AvailableNegative4284350 - 428523733023.5
sn-glycerol-3-phosphate abc transporter substrate-binding protein ugpbE9164_21140Not AvailableNegative4285344 - 428666048229.2
type ii toxin-antitoxin system death-on-curing family toxinE9164_21145Not AvailableNegative4286933 - 428730113553.8
type ii toxin-antitoxin system phd/yefm family antitoxinE9164_21150Not AvailableNegative4287298 - 42875198151.61
high-affinity branched-chain amino acid abc transporter atp-binding protein livfE9164_21155Not AvailableNegative4287683 - 428839626210.8
high-affinity branched-chain amino acid abc transporter atp-binding protein livgE9164_21160Not AvailableNegative4288398 - 428916528412.7

Displaying genes 4161 – 4170 of 5662 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total