Klebsiella pneumoniae subsp. pneumoniae strain 63

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 63 is a significant pathogen known for its role in community-acquired pneumonia (CAP). This Gram-negative bacterium exhibits a rod-shaped morphology and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, it derives energy from organic compounds, making it well-suited for its host-associated habitat. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, fitting within the mesophilic temperature range. The bacterium is motile, possessing flagella, which may contribute to its ability to colonize various niches within host organisms. Klebsiella pneumoniae subsp. pneumoniae strain 63 has a simple genomic structure, featuring one replicon and two membranes. It does not form spores, indicating a reliance on its immediate environment for survival and reproduction. In terms of biotic relationships, it is classified as free-living, suggesting that while it can inhabit hosts, it may also exist independently in other environments. Understanding the ecological role of this strain is crucial, as it is associated with significant health effects such as pneumonia. Its adaptability to varying oxygen levels and temperature, along with its motility, likely enhances its pathogenic potential in human hosts. The presence of strain 63 in clinical settings underscores the importance of monitoring this bacterium to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 63

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 63
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 63

Gene Summary

Adenine Count

1250203 bp

Thymine Count

1248591 bp

Guanine Count

1631171 bp

Cytosine Count

1641410 bp

Genome Length

5771375 bp

Protein-coding Genes

5304 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4-hydroxyproline epimeraseE9164_17015Not AvailablePositive3461816 - 346276333882.3
fad-binding oxidoreductaseE9164_17020Not AvailablePositive3462760 - 346386939854.0
(2fe-2s)-binding proteinE9164_17025Not AvailablePositive3463866 - 34641299177.15
nad(p)/fad-dependent oxidoreductaseE9164_17030Not AvailablePositive3464110 - 346537244255.5
homoprotocatechuate degradation operon regulator hparE9164_17035Not AvailableNegative3465376 - 346581616757.3
hypothetical proteinE9164_17040Not AvailablePositive3465797 - 34660459539.85
2-hydroxyhepta-2,4-diene-1,7-dioate isomeraseE9164_17045Not AvailablePositive3466103 - 346673522596.8
2-hydroxyhepta-2,4-diene-1,7-dioate isomeraseE9164_17050Not AvailablePositive3466732 - 346749628638.0
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseE9164_17055Not AvailablePositive3467493 - 346895952999.7
3,4-dihydroxyphenylacetate 2,3-dioxygenaseE9164_17060Not AvailablePositive3468961 - 346981832029.2

Displaying genes 3481 – 3490 of 5662 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total