Klebsiella pneumoniae subsp. pneumoniae strain 63

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 63 is a significant pathogen known for its role in community-acquired pneumonia (CAP). This Gram-negative bacterium exhibits a rod-shaped morphology and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, it derives energy from organic compounds, making it well-suited for its host-associated habitat. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, fitting within the mesophilic temperature range. The bacterium is motile, possessing flagella, which may contribute to its ability to colonize various niches within host organisms. Klebsiella pneumoniae subsp. pneumoniae strain 63 has a simple genomic structure, featuring one replicon and two membranes. It does not form spores, indicating a reliance on its immediate environment for survival and reproduction. In terms of biotic relationships, it is classified as free-living, suggesting that while it can inhabit hosts, it may also exist independently in other environments. Understanding the ecological role of this strain is crucial, as it is associated with significant health effects such as pneumonia. Its adaptability to varying oxygen levels and temperature, along with its motility, likely enhances its pathogenic potential in human hosts. The presence of strain 63 in clinical settings underscores the importance of monitoring this bacterium to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 63

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 63
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 63

Gene Summary

Adenine Count

1250203 bp

Thymine Count

1248591 bp

Guanine Count

1631171 bp

Cytosine Count

1641410 bp

Genome Length

5771375 bp

Protein-coding Genes

5304 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
undecaprenyldiphospho-muramoylpentapeptide beta-n-acetylglucosaminyltransferaseE9164_11720Not AvailableNegative2352537 - 235360738046.3
cell division protein ftswE9164_11725Not AvailableNegative2353604 - 235487847211.6
udp-n-acetylmuramoyl-l-alanine--d-glutamate ligaseE9164_11730Not AvailableNegative2354878 - 235619446865.6
phospho-n-acetylmuramoyl-pentapeptide- transferaseE9164_11735Not AvailableNegative2356197 - 235727939940.2
udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligaseE9164_11740Not AvailableNegative2357273 - 235863147527.9
udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2, 6-diaminopimelate ligaseE9164_11745Not AvailableNegative2358628 - 236011553345.8
peptidoglycan glycosyltransferase ftsiE9164_11750Not AvailableNegative2360102 - 236186864006.4
cell division protein ftslE9164_11755Not AvailableNegative2361884 - 236224913542.6
16s rrna (cytosine(1402)-n(4))-methyltransferase rsmhE9164_11760Not AvailableNegative2362246 - 236318734841.9
division/cell wall cluster transcriptional repressor mrazE9164_11765Not AvailableNegative2363190 - 236364817341.9

Displaying genes 2511 – 2520 of 5662 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total