Klebsiella pneumoniae subsp. pneumoniae strain 63

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 63 is a significant pathogen known for its role in community-acquired pneumonia (CAP). This Gram-negative bacterium exhibits a rod-shaped morphology and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, it derives energy from organic compounds, making it well-suited for its host-associated habitat. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, fitting within the mesophilic temperature range. The bacterium is motile, possessing flagella, which may contribute to its ability to colonize various niches within host organisms. Klebsiella pneumoniae subsp. pneumoniae strain 63 has a simple genomic structure, featuring one replicon and two membranes. It does not form spores, indicating a reliance on its immediate environment for survival and reproduction. In terms of biotic relationships, it is classified as free-living, suggesting that while it can inhabit hosts, it may also exist independently in other environments. Understanding the ecological role of this strain is crucial, as it is associated with significant health effects such as pneumonia. Its adaptability to varying oxygen levels and temperature, along with its motility, likely enhances its pathogenic potential in human hosts. The presence of strain 63 in clinical settings underscores the importance of monitoring this bacterium to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 63

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 63
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 63

Gene Summary

Adenine Count

1250203 bp

Thymine Count

1248591 bp

Guanine Count

1631171 bp

Cytosine Count

1641410 bp

Genome Length

5771375 bp

Protein-coding Genes

5304 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate abc transporter substrate-binding protein pstsE9164_08170Not AvailableNegative1653412 - 165445236732.3
glutamine--fructose-6-phosphate transaminase (isomerizing)E9164_08175Not AvailableNegative1654789 - 165661866890.4
bifunctional udp-n-acetylglucosamine diphosphorylase/glucosamine-1-phosphate n-acetyltransferase glmuE9164_08180Not AvailableNegative1656802 - 165817249060.9
hypothetical proteinE9164_08185Not AvailablePositive1658255 - 16584557303.87
f0f1 atp synthase subunit epsilonE9164_08190Not AvailableNegative1658869 - 165928815065.3
f0f1 atp synthase subunit betaE9164_08195Not AvailableNegative1659309 - 166069150213.4
f0f1 atp synthase subunit gammaE9164_08200Not AvailableNegative1660718 - 166158131515.3
f0f1 atp synthase subunit alphaE9164_08205Not AvailableNegative1661632 - 166317355172.3
f0f1 atp synthase subunit deltaE9164_08210Not AvailableNegative1663186 - 166371919531.6
f0f1 atp synthase subunit bE9164_08215Not AvailableNegative1663734 - 166420417376.0

Displaying genes 1881 – 1890 of 5662 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total