Klebsiella pneumoniae subsp. pneumoniae strain 63

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 63 is a significant pathogen known for its role in community-acquired pneumonia (CAP). This Gram-negative bacterium exhibits a rod-shaped morphology and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, it derives energy from organic compounds, making it well-suited for its host-associated habitat. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, fitting within the mesophilic temperature range. The bacterium is motile, possessing flagella, which may contribute to its ability to colonize various niches within host organisms. Klebsiella pneumoniae subsp. pneumoniae strain 63 has a simple genomic structure, featuring one replicon and two membranes. It does not form spores, indicating a reliance on its immediate environment for survival and reproduction. In terms of biotic relationships, it is classified as free-living, suggesting that while it can inhabit hosts, it may also exist independently in other environments. Understanding the ecological role of this strain is crucial, as it is associated with significant health effects such as pneumonia. Its adaptability to varying oxygen levels and temperature, along with its motility, likely enhances its pathogenic potential in human hosts. The presence of strain 63 in clinical settings underscores the importance of monitoring this bacterium to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 63

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 63
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 63

Gene Summary

Adenine Count

1250203 bp

Thymine Count

1248591 bp

Guanine Count

1631171 bp

Cytosine Count

1641410 bp

Genome Length

5771375 bp

Protein-coding Genes

5304 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf1198 family proteinE9164_07805Not AvailableNegative1582847 - 158329917328.0
hexose-6-phosphate:phosphate antiporterE9164_07810Not AvailableNegative1583436 - 158483650824.7
mfs transporterE9164_07815Not AvailableNegative1584982 - 158631048246.0
signal transduction histidine-protein kinase/phosphatase uhpbE9164_07820Not AvailableNegative1586322 - 158782455751.7
transcriptional regulator uhpaE9164_07825Not AvailableNegative1587821 - 158841421075.8
acetolactate synthase small subunitE9164_07830Not AvailableNegative1588565 - 158885210884.3
acetolactate synthase large subunitE9164_07835Not AvailableNegative1588856 - 159054460131.8
ilvb operon leader peptide ivblE9164_07840Not AvailableNegative1590649 - 15907443005.83
type i toxin-antitoxin system toxin tisbE9164_07845Not AvailablePositive1591407 - 15914963256.41
gnat family n-acetyltransferaseE9164_07850Not AvailablePositive1591587 - 159203316871.2

Displaying genes 1811 – 1820 of 5662 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total