Klebsiella pneumoniae subsp. pneumoniae strain 48

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 48 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles. It possesses flagella, indicating mobility, which may contribute to its pathogenicity. The optimal growth temperature for this strain is 37°C, aligning with the human body temperature, and it is classified as mesophilic, thriving in moderate temperature ranges. K. pneumoniae subsp. pneumoniae strain 48 has a single replicon and is structured with two membranes, typical of Gram-negative bacteria. This bacterium is notably associated with human health, causing pneumonia, particularly community-acquired pneumonia (CAP). Its ability to live freely in various host-associated environments may facilitate its transmission and infection rates. As a nonsporulating organism, it relies on other means for survival and proliferation in host environments. Understanding the ecological role of K. pneumoniae subsp. pneumoniae strain 48 highlights its adaptability and potential impact on public health, especially in community settings where the bacterium can thrive and contribute to respiratory infections. The combination of its mobility, optimal growth conditions, and pathogenic capabilities underscores the importance of monitoring and controlling its spread within populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 48

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 48
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 48

Gene Summary

Adenine Count

1223255 bp

Thymine Count

1229015 bp

Guanine Count

1638953 bp

Cytosine Count

1614120 bp

Genome Length

5705343 bp

Protein-coding Genes

5322 genes

Non-Coding Genes

296 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
copper resistance proteinE9155_24010Not AvailablePositive4859800 - 486024916273.8
peptidase m23E9155_24015Not AvailablePositive4860538 - 486127527083.2
duf2933 domain-containing proteinE9155_24020Not AvailableNegative4861309 - 48615067261.74
ag(+)-translocating p-type atpase silpE9155_24025Not AvailableNegative4861547 - 486399486905.6
hypothetical proteinE9155_24030Not AvailableNegative4864121 - 486456115494.0
cu(+)/ag(+) efflux rnd transporter permease subunit silaE9155_24035Not AvailableNegative4864648 - 4867794114657.0
cu(+)/ag(+) efflux rnd transporter periplasmic adaptor subunit silbE9155_24040Not AvailableNegative4867805 - 486909747733.3
copper abc transporter substrate-binding proteinE9155_24045Not AvailableNegative4869211 - 486956412592.1
cu(+)/ag(+) efflux rnd transporter outer membrane channel silcE9155_24050Not AvailableNegative4869593 - 487097851139.6
copper/silver response regulator transcription factor silrE9155_24055Not AvailablePositive4871168 - 487184825178.8

Displaying genes 4741 – 4750 of 5618 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total