Klebsiella pneumoniae subsp. pneumoniae strain 48

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 48 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles. It possesses flagella, indicating mobility, which may contribute to its pathogenicity. The optimal growth temperature for this strain is 37°C, aligning with the human body temperature, and it is classified as mesophilic, thriving in moderate temperature ranges. K. pneumoniae subsp. pneumoniae strain 48 has a single replicon and is structured with two membranes, typical of Gram-negative bacteria. This bacterium is notably associated with human health, causing pneumonia, particularly community-acquired pneumonia (CAP). Its ability to live freely in various host-associated environments may facilitate its transmission and infection rates. As a nonsporulating organism, it relies on other means for survival and proliferation in host environments. Understanding the ecological role of K. pneumoniae subsp. pneumoniae strain 48 highlights its adaptability and potential impact on public health, especially in community settings where the bacterium can thrive and contribute to respiratory infections. The combination of its mobility, optimal growth conditions, and pathogenic capabilities underscores the importance of monitoring and controlling its spread within populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 48

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 48
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 48

Gene Summary

Adenine Count

1223255 bp

Thymine Count

1229015 bp

Guanine Count

1638953 bp

Cytosine Count

1614120 bp

Genome Length

5705343 bp

Protein-coding Genes

5322 genes

Non-Coding Genes

296 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
two-component system response regulator baerE9155_05425Not AvailableNegative1128812 - 112953427448.3
mfs transporterE9155_05435Not AvailableNegative1131006 - 113242150697.8
multidrug efflux rnd transporter permease subunit mdtcE9155_05440Not AvailableNegative1132423 - 1135500110658.0
mdtb/muxb family multidrug efflux rnd transporter permease subunitE9155_05445Not AvailableNegative1135501 - 1138623112278.0
mdta/muxa family multidrug efflux rnd transporter periplasmic adaptor subunitE9155_05450Not AvailableNegative1138623 - 113986143395.3
dicarboxylate/amino acid:cation symporterE9155_05455Not AvailablePositive1140162 - 114143645002.4
helix-turn-helix domain-containing proteinE9155_05460Not AvailableNegative1141710 - 114232123124.2
response regulator transcription factorE9155_05465Not AvailableNegative1142815 - 114351625986.3
histidine kinaseE9155_05470Not AvailableNegative1143531 - 114538768978.8
molecular chaperoneE9155_05475Not AvailableNegative1145677 - 114702948925.6

Displaying genes 1331 – 1340 of 5618 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total