Klebsiella pneumoniae subsp. pneumoniae strain 76

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 76 is a Gram-negative, rod-shaped bacterium known for its role in causing pneumonia, specifically community-acquired pneumonia (CAP). This strain is classified as a chemoheterotroph, indicating it derives its energy from organic compounds. It exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. In terms of morphology, Klebsiella pneumoniae 76 can be found in various arrangements, including chains, pairs, and as single cells. The bacterium possesses flagella, providing it with mobility, which can facilitate its movement within host-associated habitats. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range, which is typical for many pathogenic organisms that infect warm-blooded hosts. Klebsiella pneumoniae 76 has a biotic relationship categorized as free-living, and it does not form spores. Its cellular structure includes two membranes and a single replicon, characteristics that are common among members of the Enterobacteriaceae family. The ecological role of Klebsiella pneumoniae subsp. pneumoniae strain 76 highlights its capacity to thrive in host-associated environments while also demonstrating mobility and adaptability. These traits enable the bacterium to colonize various niches within the host and potentially contribute to its pathogenicity, particularly in respiratory infections. Understanding these characteristics can provide insights into the bacterium's behavior and its implications for public health, especially in the context of pneumonia outbreaks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 76

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 76
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 76

Gene Summary

Adenine Count

1240990 bp

Thymine Count

1240365 bp

Guanine Count

1636340 bp

Cytosine Count

1646889 bp

Genome Length

5764584 bp

Protein-coding Genes

5406 genes

Non-Coding Genes

298 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
atp-dependent dethiobiotin synthetase biodE9165_23550Not AvailableNegative4770546 - 477126825566.4
malonyl-acp o-methyltransferase biocE9165_23555Not AvailableNegative4771261 - 477201627169.4
8-amino-7-oxononanoate synthaseE9165_23560Not AvailableNegative4772000 - 477315741156.0
biotin synthaseE9165_23565Not AvailableNegative4773154 - 477419438682.2
adenosylmethionine--8-amino-7-oxononanoate transaminaseE9165_23570Not AvailablePositive4774408 - 477569747059.0
kinase inhibitorE9165_23575Not AvailablePositive4775768 - 477624416906.7
amino acid permeaseE9165_23585Not AvailableNegative4776945 - 477832749666.3
histidine ammonia-lyaseE9165_23590Not AvailableNegative4778426 - 477995253934.8
urocanate hydrataseE9165_23595Not AvailableNegative4779949 - 478163761538.1
histidine utilization repressorE9165_23600Not AvailableNegative4781780 - 478250527216.5

Displaying genes 4661 – 4670 of 5704 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total